Maltose 1-phosphate

Base Information

• Chemical Name: Maltose 1-phosphate
• CAS No.: 15896-49-8
• Molecular Formula: C₁₂H₂₃O₁₄P
• Molecular Weight: 422.28
• DSSTox Substance ID: DTXSID70936024
• Nikkaji Number: J747.823B
• Wikidata: Q27132697
• Metabolomics Workbench ID: 62859
• Mol file: 15896-49-8.mol

Synonyms:Malt1P;maltose 1-phosphate;maltose-1-phosphate

Chemical Property of Maltose 1-phosphate

Chemical Property:

• Vapor Pressure: 1.65E-30mmHg at 25°C
• Boiling Point: 811.7°Cat760mmHg
• Flash Point: 444.7°C
• PSA: 245.87000
• Density: 1.89g/cm³
• LogP: -5.28020
• XLogP3: -5.8
• Hydrogen Bond Donor Count: 9
• Hydrogen Bond Acceptor Count: 14
• Rotatable Bond Count: 6
• Exact Mass: 422.08254240
• Heavy Atom Count: 27
• Complexity: 528

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OP(=O)(O)O)CO)O)O)O)O
• Isomeric SMILES: C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)OP(=O)(O)O)CO)O)O)O)O

Technology Process of Maltose 1-phosphate

There total 4 articles about Maltose 1-phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1',2',3',6',2,3,4,6-octa-O-acetyl-β-D-lactose (3616-19-1,5328-50-7,5346-90-7,6291-42-5,6920-00-9,20764-63-0,20880-60-8,20880-65-3,22352-19-8,23973-20-8,32447-69-1,34213-32-6,52554-32-2,53956-64-2,56907-29-0,56994-12-8,56994-13-9,57128-38-8,67650-36-6,68036-17-9,68036-19-1,78215-50-6,78215-51-7,79549-48-7,80446-82-8,85249-04-3,93221-83-1,93779-27-2,111407-83-1,111407-84-2,111407-85-3,120328-65-6,123809-59-6,132341-46-9,132341-47-0,132341-49-2,145307-94-4) → O4-β-D-Galactopyranosyl-O1-phosphono-β-D-glucopyranose (13168-12-2,15896-49-8,20057-11-8,52689-58-4,93221-84-2,99296-40-9,105761-60-2,105761-61-3)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen bromide; acetic acid

2: chloroform; diethyl ether; silver dihydrogenphosphate / Behandeln des Barium-Salzes des Reaktionsprodukts mit wenig Kaliummethylat in Aethanol

With silver dihydrogenphosphate; diethyl ether; chloroform; hydrogen bromide; acetic acid;

DOI:10.1021/ja01136a513

Reference yield:

α-hepta-O-acetylmaltosyl bromide (4753-07-5,5160-10-1,14206-57-6,14227-66-8,14257-35-3,67650-37-7,68682-05-3,69308-57-2,69349-74-2,70223-96-0,70223-97-1,71276-38-5,85248-99-3,118493-15-5,120575-76-0,42385-75-1) → maltose-1-phosphate (15896-49-8)

Guidance literature:

With silver orthophosphate; benzene; Behandeln des Reaktionsprodukts mit wss.-methanol. Salzsaeure;

DOI:10.1021/ja01215a003

Reference yield:

2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide (4753-07-5) → O4-β-D-Galactopyranosyl-O1-phosphono-β-D-glucopyranose (13168-12-2,15896-49-8,20057-11-8,52689-58-4,93221-84-2,99296-40-9,105761-60-2,105761-61-3)

Guidance literature:

With silver dihydrogenphosphate; diethyl ether; chloroform; Behandeln des Barium-Salzes des Reaktionsprodukts mit wenig Kaliummethylat in Aethanol;

DOI:10.1021/ja01136a513

upstream raw materials:

2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide

1',2',3',6',2,3,4,6-octa-O-acetyl-β-D-lactose

α-hepta-O-acetylmaltosyl bromide