VINTHIONINE

Base Information

• Chemical Name: VINTHIONINE
• CAS No.: 83768-87-0
• Molecular Formula: C6H11 N O2 S
• Molecular Weight: 161.24
• Mol file: 83768-87-0.mol

Synonyms:DL-Homocysteine,S-ethenyl-; S-Vinyl-DL-homocysteine

Chemical Property of VINTHIONINE

Chemical Property:

• Vapor Pressure: 0.000108mmHg at 25°C
• Refractive Index: 1.5500 (estimate)
• Boiling Point: 313.4°C at 760 mmHg
• Flash Point: 143.3°C
• PSA: 88.62000
• Density: 1.191g/cm³
• LogP: 1.36540

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of VINTHIONINE

There total 2 articles about VINTHIONINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-4-mercaptobutyric acid (454-29-5) + acetylene (74-86-2,25067-58-7) → vinyl homocysteine (83768-87-0,70858-14-9)

Guidance literature:

2-amino-4-mercaptobutyric acid; With ammonia; sodium; for 0.166667h; Sealed tube; Inert atmosphere; Cooling with ethanol-dry ice;

acetylene; In dimethyl sulfoxide; at 0 - 20 ℃; for 4h;

Reference yield:

DL-homocystine (462-10-2) + acetylene (74-86-2,25067-58-7) → vinyl homocysteine (83768-87-0,70858-14-9)

Guidance literature:

DL-homocystine; With ammonia; sodium; at -78 ℃; for 0.166667h;

acetylene; In dimethyl sulfoxide; at 0 - 20 ℃; for 4h;

DOI:10.1021/jacs.5b05950

Reference yield:

5-thio-2-nitrobenzoic acid (15139-21-6) + vinyl homocysteine (83768-87-0,70858-14-9) + ATP (56-65-5,896506-78-8) → C23H29N8O9S(1+)

Guidance literature:

With potassium chloride; ammonium bicarbonate; magnesium chloride; at 37 ℃; for 1h; Enzymatic reaction;

upstream raw materials:

2-amino-4-mercaptobutyric acid

acetylene

DL-homocystine

Refernces

• 1、 -. "Compositions and Methods for the Inhibition of Methyltransferases". Paragraph 0214. . Retrieved 2015/03/04.