Technology Process of Pentanedioic acid, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-, 1,5-diethyl
ester
There total 1 articles about Pentanedioic acid, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-, 1,5-diethyl
ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
1H-imidazole;
In
dichloromethane;
at 20 ℃;
for 16h;
DOI:10.1139/V06-073
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: NaOH / methanol / 38 h / 20 °C
1.2: 3.40 g / acetic anhydride / benzene / 1.5 h / Heating
2.1: hydroquinine anthraquinone-1,4-diyl diether / diethyl ether / 70 h / -40 °C
3.1: borane dimethyl sulfide complex / tetrahydrofuran / 15 h / 20 °C
4.1: 79 percent / 4-methylmorpholine N-oxide; tetrapropylammonium perruthenate; molecular sieves 4 Angstroem / CH2Cl2; acetonitrile / 0.5 h / 20 °C
5.1: NaH / tetrahydrofuran / 0.33 h / 20 °C
5.2: 3.50 g / tetrahydrofuran / -78 - 20 °C
6.1: MonoPhosTM / Rh(acac)(eth)2 / 83 °C
7.1: toluene / 1.5 h / Heating
8.1: NaH / tetrahydrofuran / 0.33 h / 0 °C
8.2: tetrahydrofuran / 0 - 20 °C
9.1: [(η3-C3H5)PdCl]2; 1,1'-bis(diphenylphosphino)ferrocene / tetrahydrofuran / 0.33 h / 100 °C / microwave irradiation
With
sodium hydroxide; tetrapropylammonium perruthennate; hydroquinine anthraquinone-1,4-diyl diether; dimethylsulfide borane complex; 4 A molecular sieve; MonoPhosTM; sodium hydride; 4-methylmorpholine N-oxide;
1,1'-bis-(diphenylphosphino)ferrocene; bis(η3-allyl-μ-chloropalladium(II)); Rh(acac)(eth)2;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene; acetonitrile;
4.1: Ley-Griffith oxidation / 5.2: Horner-Wadsworth-Emmons reaction;
DOI:10.1139/V06-073
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: NaOH / methanol / 38 h / 20 °C
1.2: 3.40 g / acetic anhydride / benzene / 1.5 h / Heating
2.1: hydroquinine anthraquinone-1,4-diyl diether / diethyl ether / 70 h / -40 °C
3.1: borane dimethyl sulfide complex / tetrahydrofuran / 15 h / 20 °C
4.1: 79 percent / 4-methylmorpholine N-oxide; tetrapropylammonium perruthenate; molecular sieves 4 Angstroem / CH2Cl2; acetonitrile / 0.5 h / 20 °C
5.1: NaH / tetrahydrofuran / 0.33 h / 20 °C
5.2: 3.50 g / tetrahydrofuran / -78 - 20 °C
6.1: MonoPhosTM / Rh(acac)(eth)2 / 83 °C
7.1: toluene / 1.5 h / Heating
8.1: NaH / tetrahydrofuran / 0.33 h / 0 °C
8.2: tetrahydrofuran / 0 - 20 °C
9.1: [(η3-C3H5)PdCl]2; 1,1'-bis(diphenylphosphino)ferrocene / tetrahydrofuran / 0.33 h / 100 °C / microwave irradiation
With
sodium hydroxide; tetrapropylammonium perruthennate; hydroquinine anthraquinone-1,4-diyl diether; dimethylsulfide borane complex; 4 A molecular sieve; MonoPhosTM; sodium hydride; 4-methylmorpholine N-oxide;
1,1'-bis-(diphenylphosphino)ferrocene; bis(η3-allyl-μ-chloropalladium(II)); Rh(acac)(eth)2;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene; acetonitrile;
4.1: Ley-Griffith oxidation / 5.2: Horner-Wadsworth-Emmons reaction;
DOI:10.1139/V06-073