9-benzyl-9H-purine

Base Information

• Chemical Name: 9-benzyl-9H-purine
• CAS No.: 25491-56-9
• Molecular Formula: C12H10 N4
• Molecular Weight: 210.238
• Mol file: 25491-56-9.mol

Synonyms:9H-Purine,9-benzyl- (6CI,8CI); 9-Benzyl-9H-purine; 9-Benzylpurine; NSC 35001; SQ 23206

Chemical Property of 9-benzyl-9H-purine

Chemical Property:

• Vapor Pressure: 5.84E-07mmHg at 25°C
• Boiling Point: 410.8°C at 760 mmHg
• Flash Point: 202.3°C
• Density: 1.27g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9-benzyl-9H-purine

There total 22 articles about 9-benzyl-9H-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

9-benzyl-6-mercaptopurine (17447-84-6) → 9-benzyl-9H-purine (25491-56-9)

Guidance literature:

With nitric acid; In water; at 50 ℃; for 1h;

DOI:10.1080/10426507.2016.1225057

Reference yield: 93.0%

9-benzyl-6-hydrazino-9H-purine (6268-73-1) → 9-benzyl-9H-purine (25491-56-9)

Guidance literature:

With water; oxygen; copper(II) sulfate; at 80 ℃; for 6h; Reagent/catalyst; Concentration; Temperature; Time; Catalytic behavior; Green chemistry;

DOI:10.1039/c3gc41658e

Reference yield: 89.0%

9-benzyl-6-(propylthio)-9H-purine (1345837-80-0) → 9-benzyl-9H-purine (25491-56-9)

Guidance literature:

With triethylsilane; palladium 10% on activated carbon; In tetrahydrofuran; at 0 - 20 ℃; for 1.75h; chemoselective reaction;

DOI:10.1021/ol2026813

upstream raw materials:

purine

benzyl alcohol

9-benzyl-6-iodo-9H-purine

9-benzyl-2,6-bis(ethoxycarbonyl)purine

Downstream raw materials:

9-benzyl-8-bromo-9H-purine

9-benzyl-8-(1-ethoxyvinyl)purine

9-benzyl-6-phenyl-9H-purine

Refernces

• 1、 Gordon, Malcolm R.,Lindell, Stephen D.. "Microwave promoted reaction of purin-6-yl magnesium halides with aldehydes in dichloromethane at 100u202f°C". . p. 1945 - 1947. Retrieved 2018.
• 2、 Xia, Ran,Xie, Ming-Sheng,Niu, Hong-Ying,Qu, Gui-Rong,Guo, Hai-Ming. "Efficient synthesis of nebularine and vidarabine via dehydrazination of (hetero)aromatics catalyzed by CuSO4 in water". . p. 1077 - 1081. Retrieved 2014/03/21.