Sandaracopimarinol

Base Information

• Chemical Name: Sandaracopimarinol
• CAS No.: 24563-84-6
• Molecular Formula: C20H32 O
• Molecular Weight: 288.473
• Mol file: 24563-84-6.mol

Synonyms:1-Phenanthrenemethanol,7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-trimethyl-, [1R-(1a,4ab,4ba,7a,10aa)]-; Podocarp-8(14)-en-15-ol, 13b-methyl-13-vinyl- (7CI);Podocarp-8(14)-en-15-ol, 7b-methyl-7-vinyl- (8CI); 8(14),15-Isopimaradien-18-ol; Isopimarinol;Sandaracopimaradienol; Sandaracopimarinol; Sandaracopimarol

Chemical Property of Sandaracopimarinol

Chemical Property:

• Melting Point: 84-86 °C
• Boiling Point: 378.7±21.0 °C(Predicted)
• PKA: 14.96±0.10(Predicted)
• PSA: 20.23000
• Density: 0.99±0.1 g/cm3(Predicted)
• LogP: 5.11390

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Sandaracopimarinol

There total 7 articles about Sandaracopimarinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sandaracopimaradiene (1686-61-9,5956-33-2,17123-77-2,19882-10-1,21738-16-9,71030-08-5,1686-56-2) → sandaracopimara-8(14),15-dien-18-ol (24563-84-6)

Guidance literature:

With cytochrome P₄₅₀ (CYP) mono-oxygenase CYP₅₀₃C₁ from A_. niger; In aq. phosphate buffer; at 16 ℃; for 72h; pH=7; Enzymatic reaction;

DOI:10.1021/acs.jnatprod.6b00764

Reference yield:

→ (+/-)-Sandaracopimaradien-19-ol (1686-59-5,4616-38-0,19882-09-8,24563-84-6,30211-91-7,110052-38-5)

Guidance literature:

Methyl-(+-)-4-episandaracopimarat (VIb), LiAlH4;

Reference yield:

methyl sandaracopimarate (1686-54-0) → sandaracopimara-8(14),15-dien-18-ol (24563-84-6)

Guidance literature:

(reduction);

DOI:10.1139/v69-726

upstream raw materials:

sandaracopimaric acid

methyl sandaracopimarate

sandaracopimar-18-yl acetate

(E,E,E)-geranylgeranyl diphosphate

Downstream raw materials:

16-tert-butyldiphenylsilyloxy-13-epi-pimar-8⁽¹⁴⁾-en-18-ol, acetate

(1R,4aR,4bS,7R,10aR)-1,4a,7-Trimethyl-1-phenylsulfanylmethyl-7-vinyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-phenanthrene

sandaracopimaradiene

sandaracopimarinal

Refernces

• 1、 Kuthan,J. et al.. "-". . p. 2215 - 2220. Retrieved 1967.
• 2、 Chu, Min,Coates, Robert M.. "Partial Synthesis of 9,10-Syn Diterpenes via Tosylhydrazone Reduction: (-)-(9β)-Pimara-7,15-diene and (-)-(9β)-Isopimaradiene". . p. 4590 - 4597. Retrieved 2007/10/02.
• 3、 Raldugin, V. A.,Demenkova, L. I.,Pentegova, V. A.. "Labdane acids and other components of the needles of Pinus pumila". . p. 192 - 197. Retrieved 2007/10/02.