2-Chloroethyl phenyl sulfone

Base Information

• Chemical Name: 2-Chloroethyl phenyl sulfone
• CAS No.: 938-09-0
• Molecular Formula: C8H9ClO2S
• Molecular Weight: 204.677
• Hs Code.: 2904909090
• European Community (EC) Number: 213-337-5
• NSC Number: 145234,236821,207409
• UNII: EVR4295G77
• DSSTox Substance ID: DTXSID60239652
• Nikkaji Number: J145.074C
• Wikidata: Q72449795
• ChEMBL ID: CHEMBL288134
• Mol file: 938-09-0.mol

Synonyms:2-Chloroethyl phenyl sulfone;938-09-0;2-Chloroethylsulfonylbenzene;(2-chloroethylsulfonyl)benzene;(2-chloroethanesulfonyl)benzene;Sulfone, 2-chloroethyl phenyl;[(2-Chloroethyl)sulfonyl]benzene;Benzene, [(2-chloroethyl)sulfonyl]-;2-Chloroethyl phenyl sulphone;((2-Chloroethyl)sulphonyl)benzene;2-chloroethylphenyl sulfone;((2-CHLOROETHYL)SULFONYL)BENZENE;[(2-Chloroethyl)sulphonyl]benzene;EINECS 213-337-5;NSC-145234;NSC-207409;NSC-236821;Benzene, ((2-chloroethyl)sulfonyl)-;2-Chloroethylphenylsulfone;Phenyl 2-chloroethyl sulfone;(2-chloroethyl)-phenylsulfone;SCHEMBL798585;beta-Chloroethyl phenyl sulfone;Phenyl beta-chloroethyl sulfone;CHEMBL288134;(beta-chloroethylsulfonyl)benzene;1-chloro-2-phenylsulphonylethane;2-(Phenylsulfonyl)ethyl chloride;NUJGORANFDSMOL-UHFFFAOYSA-;DTXSID60239652;EVR4295G77;1-Chloro-2-(phenylsulfonyl)ethane;CS-M0047;STR07209;[(2-Chloroethyl)sulfonyl]benzene #;Benzene,[(2-chloroethyl)sulfonyl]-;MFCD00025047;NSC145234;NSC207409;NSC236821;STK760846;AKOS005199255;NSC 145234;NSC 207409;NSC 236821;(2-chloroethyl)(dioxo)phenyl-lambda-sulfane;FT-0611946;EN300-22271;Z147642528;TERT-BUTYL7-HYDROXY-3,4-DIHYDROQUINOLINE-1(2H)-CARBOXYLATE

Chemical Property of 2-Chloroethyl phenyl sulfone

Chemical Property:

• Vapor Pressure: 5.18E-05mmHg at 25°C
• Melting Point: 55-57 °C(lit.)
• Refractive Index: 1.536
• Boiling Point: 358.7 °C at 760 mmHg
• Flash Point: 170.7 °C
• PSA: 42.52000
• Density: 1.286 g/cm³
• LogP: 2.77990
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 204.0011784
• Heavy Atom Count: 12
• Complexity: 212

Purity/Quality:

99% ^*data from raw suppliers

2-Chloroethyl Phenyl Sulfone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T,C
• Statements: 23/24/25
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)S(=O)(=O)CCCl

Technology Process of 2-Chloroethyl phenyl sulfone

There total 20 articles about 2-Chloroethyl phenyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

m-chloroperoxybenzoic acid (64741-01-1) + 2-Chloroethyl phenyl sulfide (5535-49-9) → 2-chloroethyl phenyl sulfone (938-09-0)

Guidance literature:

In dichloromethane;

Reference yield: 95.0%

2-Chloroethyl phenyl sulfide (5535-49-9) → 2-chloroethyl phenyl sulfone (938-09-0)

Guidance literature:

With dihydrogen peroxide; tungsten(VI) oxide; In methanol; water; at 60 ℃; for 12h;

DOI:10.1021/ol052019i

Reference yield: 92.0%

2-Chloroethyl phenyl sulfide (5535-49-9) → 2-chloroethyl phenyl sulfone (938-09-0) + chloroethyl phenyl sulfoxide (27998-60-3)

Guidance literature:

With dihydrogen peroxide; tungsten(VI) oxide; In methanol; water; at 25 ℃; for 4h;

DOI:10.1021/ol052019i

upstream raw materials:

2-(phenylthio)ethanol

2-Chloroethyl phenyl sulfide

2-(phenylsulfonyl)ethanol

sodium benzenesulfonate

Downstream raw materials:

ethanol

Benzenesulfinic acid

N-(2-benzenesulfonyl-ethyl)-phthalimide

{[2-(benzylsulfanyl)ethyl]sulfonyl}benzene

Refernces

• 1、 Picard, Baptiste,Gouilleux, Boris,Lebleu, Thomas,Maddaluno, Jacques,Chataigner, Isabelle,Penhoat, Ma?l,Felpin, Fran?ois-Xavier,Giraudeau, Patrick,Legros, Julien. "Oxidative Neutralization of Mustard-Gas Simulants in an On-Board Flow Device with In-Line NMR Monitoring". supporting information. p. 7568 - 7572. Retrieved 2017/06/13.
• 2、 Padmavathi, Venkatapuram,Venkatesh, Bhumireddy Chinnachennaiahgari,Premakumari, Chokkappagari,Padmaja, Adivireddy. "Synthesis of a new class of arylsulfonylethylsulfonylmethyloxazolines and thiazolines". . p. 646 - 651. Retrieved 2012/09/07.