delta-guanidinovaleric acid

Base Information

• Chemical Name: delta-guanidinovaleric acid
• CAS No.: 462-93-1
• Molecular Formula: C6H13 N3 O2
• Molecular Weight: 159.188
• Hs Code.: 2925290090
• Mol file: 462-93-1.mol

Synonyms:Valericacid, 5-guanidino- (6CI,7CI,8CI); 5-Guanidinovaleric acid; HL 6439;N-(5-Pentanoic acid)guanidine; d-Guanidinovaleric acid

Chemical Property of delta-guanidinovaleric acid

Chemical Property:

• Vapor Pressure: 8.37E-07mmHg at 25°C
• Melting Point: 265-266 °C (decomp)
• Boiling Point: 379.4°Cat760mmHg
• PKA: 4.68±0.10(Predicted)
• Flash Point: 183.2°C
• PSA: 99.20000
• Density: 1.3g/cm³
• LogP: 0.91530

Purity/Quality:

98%min ^*data from raw suppliers

5-Guanidinopentanoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of delta-guanidinovaleric acid

There total 1 articles about delta-guanidinovaleric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 5-guanidinopentanoic acid (462-93-1) + D,L-histidine (71-00-1)

Guidance literature:

Reference yield:

Paramax Wang resin + 5-guanidinopentanoic acid (462-93-1) + N-(fluoren-9-ylmethoxycarbonyl)glycine (29022-11-5) + Fmoc-Leu-OH (35661-60-0) + Fmoc-Pro-OH (71989-31-6) + Fmoc-Tyr(Bzl)-OH (71989-40-7) + Fmoc-Lys-OH (105047-45-8) + N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine (73724-45-5) + Fmoc-L-Arg-OH (91000-69-0,130752-32-8) + 2-(9H-fluoren-9-ylmethoxycarbonylamino)-pent-4-enoic acid (146549-21-5) → C65H98N17O14Pol

Guidance literature:

Paramax Wang resin; Fmoc-Tyr(Bzl)-OH; With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; wang resin

With piperidine; In N,N-dimethyl-formamide;

5-guanidinopentanoic acid; N-(fluoren-9-ylmethoxycarbonyl)glycine; Fmoc-Leu-OH; Fmoc-Pro-OH; Fmoc-Lys-OH; N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine; Fmoc-L-Arg-OH; 2-(9H-fluoren-9-ylmethoxycarbonylamino)-pent-4-enoic acid; Further stages;

DOI:10.1039/c6ob02247b

Reference yield:

2-mesitylenesulphonyl chloride (773-64-8) + 5-guanidinopentanoic acid (462-93-1) → 5-(3-(mesitylsulfonyl)guanidino)pentanoic acid

Guidance literature:

With sodium hydroxide; In water; acetone; at 20 ℃; for 2h;

DOI:10.1016/j.bmc.2022.116616

Refernces