Tris(4-aminophenyl)methane

Base Information

• Chemical Name: Tris(4-aminophenyl)methane
• CAS No.: 548-61-8
• Molecular Formula: C19H19 N3
• Molecular Weight: 289.38
• Hs Code.: 2921420090
• European Community (EC) Number: 208-952-0
• UNII: HF739T3GE5
• DSSTox Substance ID: DTXSID10203282
• Nikkaji Number: J6.450E
• Wikidata: Q72514938
• ChEMBL ID: CHEMBL491772
• Mol file: 548-61-8.mol

Synonyms:548-61-8;Tris(4-aminophenyl)methane;4,4',4''-methanetriyltrianiline;4-[bis(4-aminophenyl)methyl]aniline;Leucoparafuchsin;Leucoparafuchsine;Leucopararosaniline;4,4',4''-Methylidynetrianiline;Triaminotriphenylmethane;p,p',p''-Triaminotriphenylmethane;4,4',4''-Triaminotriphenylmethane;BRN 2811314;Methane, tris(4-aminophenyl)-;Tris-4-aminofenylmethan [Czech];Tris-4-aminofenylmethan;C19H19N3;EINECS 208-952-0;Aniline, 4,4',4''-methylidynetri-;4,4',4''-Methylidynetrisbenzeneamine;Benzenamine, 4,4',4''-methylidynetris-;Benzeneamine, 4,4',4''-methylidynetris-;HF739T3GE5;EC 208-952-0;Benzeneamine, 4,4',4''-methylidynetris- (9CI);4-13-00-00525 (Beilstein Handbook Reference);Tris(4-aminophenyl)-methane;Leucoaniline;Paraleukanilin;Tris(p-aminophenyl)methane;tris-(4-aminophenyl)methane;UNII-HF739T3GE5;SCHEMBL223522;triphenylmethane derivative, 8;CHEMBL491772;YSCK0037;4,4',4'-Methanetriyltrianiline;BDBM29336;DTXSID10203282;HY-D0306;MFCD00137820;AKOS016009861;4,4'',4''''-Methanetriyltrianiline;4,4\',4\'\'-Methanetriyltrianiline;CS-W009097;SB82218;CS-13020;LS-90437;T3599;EN300-6477090;A870340;SR-01000004767;SR-01000004767-1;W-109561;Z276544214

Chemical Property of Tris(4-aminophenyl)methane

Chemical Property:

• Vapor Pressure: 0Pa at 25℃
• Melting Point: 208°C(lit.)
• Refractive Index: 1.5800 (estimate)
• Boiling Point: 540.9°Cat760mmHg
• PKA: 5.56±0.25(Predicted)
• Flash Point: 316.7°C
• PSA: 78.06000
• Density: 1.208g/cm³
• LogP: 5.35700
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: soluble in Methanol
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 289.157897619
• Heavy Atom Count: 22
• Complexity: 269

Purity/Quality:

99.9% ^*data from raw suppliers

4,4'',4''''-Methanetriyltrianiline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(C2=CC=C(C=C2)N)C3=CC=C(C=C3)N)N
• Uses: tris(4-aminophenyl)methane is mainly used in the manufacture of poly isocyanate adhesive and polymer isocyanate adhesive is a rubber and metal or a non metal material is the best binder of rubber with various woven objects (natural or synthetic fiber) and leather adhesive is particularly suitable. Polymer isocyanate adhesive is a compound containing isocyanate group (- NCO) can interact with a variety of chemical groups (- Oh, - H, - NH2 or unsaturated substances), thereby the object firmly bonded together and adhesion is quite good, usually at or more than desire bonded non metal material strength. After bonding, the intrinsic bonding force can be maintained at high temperature and moisture, and it is welcomed by users.. Now widely used in aviation machinery, petrochemical, electronic machinery, transportation, construction, light industry and other departments. 4,4'',4''''-Methanetriyltrianiline is an inhibitor of hepatitis C virus helicase. 4,4'',4''''-Methanetriyltrianiline has a carcinogenic activity and increases the incidence of tumors in the recticuloendothelial system of animals.

Technology Process of Tris(4-aminophenyl)methane

There total 32 articles about Tris(4-aminophenyl)methane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

basic red 9 (569-61-9,131883-55-1,187112-40-9) → 4,4',4''-triaminotriphenylmethane (548-61-8)

Guidance literature:

With sodium disulfite; zinc; In ethanol; for 3h; Heating;

Reference yield: 79.0%

pararosaniline (467-62-9) → 4,4',4''-triaminotriphenylmethane (548-61-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; for 12h;

DOI:10.1002/1099-0690(200011)2000:22<3787::aid-ejoc3787>3.0.co;2-0

Reference yield:

Bromoform (75-25-2) + aniline (62-53-3) → pararosaniline (467-62-9) + 4,4',4''-triaminotriphenylmethane (548-61-8)

Guidance literature:

at 125 - 130 ℃;

upstream raw materials:

aurin

pararosaniline

4.4'-diamino-diphenylcarbinol

aniline hydrochloride

Downstream raw materials:

pararosaniline

tris(4-isocyanatophenyl)-methane

tris-(4-acetylamino-phenyl)-methane

C₂₂H₁₃N₃S₃

Refernces

• 1、 Shukla, Swapnil,Mahata, Arup,Pathak, Biswarup,Lochab, Bimlesh. "Cardanol benzoxazines-interplay of oxazine functionality (mono to tetra) and properties". . p. 78071 - 78080. Retrieved 2015.
• 2、 Houjou, Hirohiko,Koga, Tatsuya,Akiizumi, Midori,Yoshikawa, Isao,Araki, Koji. "Synthesis and structural analysis of triphenylmethane-based alkanecarboxamides and their assembly into nanometer-size fibrous objects". experimental part. p. 730 - 736. Retrieved 2009/12/06.