2,2,2-Trichloro-2,2-dihydro-1,3,2-benzodioxaphosphole

Base Information

• Chemical Name: 2,2,2-Trichloro-2,2-dihydro-1,3,2-benzodioxaphosphole
• CAS No.: 2007-97-8
• Molecular Formula: C6H4Cl3O2P
• Molecular Weight: 245.429
• European Community (EC) Number: 217-913-7
• DSSTox Substance ID: DTXSID20942094
• Nikkaji Number: J199.816A
• Wikidata: Q82919065
• Mol file: 2007-97-8.mol

Synonyms:2007-97-8;1,2-Phenylene phosphorotrichloridite;2,2,2-Trichloro-2,2-dihydro-1,3,2-benzodioxaphosphole;EINECS 217-913-7;2,2,2-trichloro-1,3,2lambda5-benzodioxaphosphole;1,3,2-Benzodioxaphosphole, 2,2,2-trichloro-;1,3,2-Benzodioxaphosphole, 2,2,2-trichloro-2,2-dihydro-;2,2,2-trichloro-2lambda5-benzo[d][1,3,2]dioxaphosphole;Catechylphosphorotrichloride;SCHEMBL356873;DTXSID20942094;MFCD00014578;AKOS015957644;2,2,2-trichlorobenzo-1,3,2-dioxaphosphole;CS-0206613;FT-0609025;1,3,2-Benzodioxaphosphole,2,2,2-trichloro-;2,2,2-Trichloro-2H-1,3,2lambda~5~-benzodioxaphosphole;F9995-0148

Chemical Property of 2,2,2-Trichloro-2,2-dihydro-1,3,2-benzodioxaphosphole

Chemical Property:

• Melting Point: 48-50 °C
• Boiling Point: 102-104 °C 2mm
• Flash Point: 102-104°C/2mm
• PSA: 32.05000
• LogP: 4.30250
• Sensitive.: Moisture Sensitive
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 243.901449
• Heavy Atom Count: 12
• Complexity: 185

Purity/Quality:

98%min ^*data from raw suppliers

CATECHYLPHOSPHOROTRICHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R34:Causes burns.
• Hazard Codes: R34:Causes burns.
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)OP(O2)(Cl)(Cl)Cl

Technology Process of 2,2,2-Trichloro-2,2-dihydro-1,3,2-benzodioxaphosphole

There total 6 articles about 2,2,2-Trichloro-2,2-dihydro-1,3,2-benzodioxaphosphole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

dichloro(2-methoxyphenoxy)phosphine (137018-66-7) → trichloro(o-phenylenedioxy)phosphorane (2007-97-8)

Guidance literature:

With chlorine; In dichloromethane; at -15 ℃;

Reference yield: 65.0%

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → trichloro(o-phenylenedioxy)phosphorane (2007-97-8)

Guidance literature:

With phosphorus pentachloride; In benzene; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.jorganchem.2020.121313

Reference yield:

pyrocatechol phosphorochloridite (1641-40-3) → trichloro(o-phenylenedioxy)phosphorane (2007-97-8)

Guidance literature:

With chlorine;

upstream raw materials:

benzene-1,2-diol

dichloro(2-methoxyphenoxy)phosphine

pyrocatechol phosphorochloridite

phosphorus pentachloride

Downstream raw materials:

o-phenylene chlorophosphate

diethyl chlorophosphate

6-chloro-2-hydroxy-4-phenylbenzo[e][1,2λ⁵]oxaphosphinine 2-oxide

Refernces

• 1、 Tatarinov,Terekhova,Voloshina,Sapunova,Lyubina,Mironov. "Synthesis and Antimicrobial Activity of New Dialkyl(diaryl)-2-(5-chloro-2-hydroxyphenyl)-2-(phenylethenyl)pentylphosphonium Salts". . p. 1800 - 1805. Retrieved 2018/11/24.
• 2、 Konovalova, I.V.,Gloede, J.,Mironov, V.F.. "SYNTHESIS AND PROPERTIES OF 2-HEXAFLUOROISOPROPOXY-1,3,2λ5-BENZODIOXAPHOSPHOLANE 2,2-DIHALIDES". . p. 1208 - 1209. Retrieved 2007/10/02.