2,4,5-TRICHLOROBIPHENYL

Base Information

• Chemical Name: 2,4,5-TRICHLOROBIPHENYL
• CAS No.: 15862-07-4
• Molecular Formula: C12H7 Cl3
• Molecular Weight: 257.547
• Hs Code.: 2903999010
• Mol file: 15862-07-4.mol

Synonyms:Biphenyl,2,4,5-trichloro- (8CI); 2,4,5-Trichloro-1,1'-biphenyl; 2,4,5-Trichlorobiphenyl;PCB 29

Chemical Property of 2,4,5-TRICHLOROBIPHENYL

Chemical Property:

• Vapor Pressure: 0.000297mmHg at 25°C
• Melting Point: 80℃
• Refractive Index: 1.6040 (rough estimate)
• Boiling Point: 331.6 °C at 760 mmHg
• Flash Point: 227.4 °C
• PSA: 0.00000
• Density: 1.351 g/cm³
• LogP: 5.31380
• Water Solubility.: 0.14mg/L(25 oC)

Purity/Quality:

98%Min ^*data from raw suppliers

2,4,5-Trichlorobiphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s): N
• Hazard Codes: N
• Statements: 33-50/53
• Safety Statements: 35-60-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 2,4,5-Trichlorobiphenyl is a polychlorinated biphenyl (PCB) congeners.

Technology Process of 2,4,5-TRICHLOROBIPHENYL

There total 16 articles about 2,4,5-TRICHLOROBIPHENYL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

1,2,4,5-tetrachlorobenzene (95-94-3) + phenylboronic acid (98-80-6) → 2,4,5-trichlorobiphenyl (15862-07-4)

Guidance literature:

With potassium phosphate; tri-tert-butyl phosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In toluene; at 80 ℃; for 24h;

DOI:10.1007/s11172-005-0342-0

Reference yield: 52.0%

bromobenzene (108-86-1,52753-63-6) + 1,2,4,5-tetrachlorobenzene (95-94-3) → biphenyl (92-52-4,1594-86-1) + 2,4,5-trichlorobiphenyl (15862-07-4) + 2,2',4,4',5,5'-Hexachlorobiphenyl (35065-27-1,51908-10-2)

Guidance literature:

bromobenzene; With n-butyllithium; In tetrahydrofuran; hexane; for 0.333333h; cooling;

With zinc(II) chloride; In tetrahydrofuran; hexane; at 20 ℃; for 0.333333h;

1,2,4,5-tetrachlorobenzene; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; hexane; for 24h; Heating;

DOI:10.1007/s11172-005-0342-0

Reference yield: 52.0%

2,4,5-trichloroiodobenzene (7145-82-6) + phenylboronic acid (98-80-6) → 2,4,5-trichlorobiphenyl (15862-07-4)

Guidance literature:

With sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; ethanol; for 40h; Heating;

DOI:10.1016/j.chemosphere.2004.04.035

upstream raw materials:

2,4,5-trichloroaniline

benzene

2.4.5-Trichlor-N-nitroso-acetanilid

1,2,4,5-tetrachlorobenzene

Downstream raw materials:

biphenyl

2-chloro-1,1'-biphenyl

PCB 7

ethylbenzene

Refernces

• 1、 Burukin,Vasil'ev,Chizhov,Zlotin. "Cross-coupling of polychloroarenes with phenylboronic acid and organozinc compounds catalyzed by palladium complexes". . p. 970 - 974. Retrieved 2005.
• 2、 Groombridge, Benjamin J.,Goldup, Stephen M.,Larrosa, Igor. "Selective and general exhaustive cross-coupling of di-chloroarenes with a deficit of nucleophiles mediated by a Pd-NHC complex". supporting information. p. 3832 - 3834. Retrieved 2015/03/30.
• 3、 Burukin,Vasil'Ev,Merkulova,Chizhov,Mistryukov,Zlotin. "Cross-coupling of polychlorobenzenes with phenylboronic acid in the presence of [Pd]-imidazolium salts as catalytic systems". . p. 1467 - 1469. Retrieved 2008/09/18.