Trimethylolpropane phosphite

Base Information

• Chemical Name: Trimethylolpropane phosphite
• CAS No.: 824-11-3
• Deprecated CAS: 29267-12-7
• Molecular Formula: C6H11 O3 P
• Molecular Weight: 162.125
• European Community (EC) Number: 212-523-3
• NSC Number: 127561
• UN Number: 3464
• UNII: 1ND7080ZYD
• DSSTox Substance ID: DTXSID10871809
• Nikkaji Number: J50.814D
• Wikipedia: Trimethylolpropane_phosphite
• Wikidata: Q7842218
• Mol file: 824-11-3.mol

Synonyms:EPTBO;TMPP (phosphite);trimethylolpropane phosphite

Chemical Property of Trimethylolpropane phosphite

Chemical Property:

• Vapor Pressure: 5.48mmHg at 25°C
• Melting Point: 50-55 °C
• Boiling Point: 147.9°C at 760 mmHg
• Flash Point: 44.8°C
• PSA: 41.28000
• LogP: 1.68670
• Water Solubility.: Insoluble in water
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 162.04458121
• Heavy Atom Count: 10
• Complexity: 117
• Transport DOT Label: Poison

Purity/Quality:

98%,99%, ^*data from raw suppliers

Trimethylolpropane Phosphite >94.0%(T) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T+
• Statements: 21-28
• Safety Statements: 28-36/37-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCC12COP(OC1)OC2

Technology Process of Trimethylolpropane phosphite

There total 8 articles about Trimethylolpropane phosphite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.5%

1,1,1-tri(hydroxymethyl)propane (77-99-6) → ethriol phosphite (824-11-3)

Guidance literature:

With phosphorus trichloride; In Petroleum ether; at -5 - 20 ℃; Concentration; Solvent; Inert atmosphere; Large scale;

Reference yield: 65.0%

1,1,1-tri(hydroxymethyl)propane (77-99-6) + triethyl phosphite (122-52-1) → ethriol phosphite (824-11-3)

Guidance literature:

With triethylamine; at 100 ℃;

Reference yield:

C10H17N2O5P → diazoacetic acid ethyl ester (623-73-4) + ethriol phosphite (824-11-3)

Guidance literature:

at 45 ℃; Rate constant;

upstream raw materials:

1,1,1-tri(hydroxymethyl)propane

triethyl phosphite

trimethylphosphane

Downstream raw materials:

methyl-(5-ethyl-2-methyl-1,3,2-dioxaphosphorinan-5-yl)methyl methyl ester (P-oxide phosphonate)

Os3(CO)8(P(OCH2)3CEt)(μ-C4Ph4)

Ru₃(CO)9(P(OCH₂)3CC₂H₅)(CNC(CH₃)3)(As(C₆H₅)3)

Ru₃(CO)9(P(OCH₂)3CC₂H₅)2(CNC(CH₃)3)

Refernces

• 1、 Mei, Jiajun,Pardue, Daniel B.,Kalman, Steven E.,Gunnoe, T. Brent,Cundari, Thomas R.,Sabat, Michal. "Oxygen atom insertion into iron(II) phenyl and methyl bonds: A key step for catalytic hydrocarbon functionalization". supporting information. p. 5597 - 5605. Retrieved 2015/02/19.