Technology Process of Delartine
There total 2 articles about Delartine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 4.8 mg / NaBH3CN / methanol / 1 h
2: 4.6 mg / K2CO3 / dimethylformamide / 72 h / Ambient temperature
With
sodium cyanoborohydride; potassium carbonate;
In
methanol; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 73 percent / Hg(OAc)2, 2.5percent aq. AcOH / 1.) reflux, 1 h, 2.) RT, overnight
2: 4.6 mg / K2CO3 / dimethylformamide / 72 h / Ambient temperature
With
mercury(II) diacetate; potassium carbonate; acetic acid;
In
N,N-dimethyl-formamide;
- Guidance literature:
-
With
potassium hydroxide;
In
ethanol;
at 20 ℃;
for 13h;
DOI:10.1021/jm9604991