Technology Process of Urea, [(4-bromobenzo[b]thien-2-yl)methyl]-
There total 8 articles about Urea, [(4-bromobenzo[b]thien-2-yl)methyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
In
water;
at 80 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 91 percent / bromine, anhydreous sodium acetate / acetic acid / roomtemp., 1 h, then 15 min heating
3: 95 percent / 50percent sulphuric acid / acetic acid / reflux, 8h, then room temp.
4: 1) thionylchloride, 2) conc. ammonia / 1) benzene, reflux, 2) ether, 30 min
5: 80 percent / LAH, aluminium chloride / diethyl ether / 26 h / Heating
6: 88 percent / H2O / 2 h / 80 °C
With
ammonium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; thionyl chloride; sulfuric acid; bromine; sodium acetate;
In
diethyl ether; water; acetic acid;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 95 percent / 50percent sulphuric acid / acetic acid / reflux, 8h, then room temp.
2: 1) thionylchloride, 2) conc. ammonia / 1) benzene, reflux, 2) ether, 30 min
3: 80 percent / LAH, aluminium chloride / diethyl ether / 26 h / Heating
4: 88 percent / H2O / 2 h / 80 °C
With
ammonium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; thionyl chloride; sulfuric acid;
In
diethyl ether; water; acetic acid;