Solifenacin hydrochloride

Base Information

• Chemical Name: Solifenacin hydrochloride
• CAS No.: 180468-39-7
• Molecular Formula: C23H26 N2 O2 . Cl H
• Molecular Weight: 398.931
• DSSTox Substance ID: DTXSID4046783
• ChEMBL ID: CHEMBL2361425
• Mol file: 180468-39-7.mol

Synonyms:Solifenacin hydrochloride;180468-39-7;Solifenacin (hydrochloride);Solifenacin HCl;YM905 hydrochloride;Vesicare;DTXSID4046783;[(3R)-1-azabicyclo[2.2.2]octan-3-yl] (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate;hydrochloride;2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester, hydrochloride (1:1), (1S)-;NCGC00168778-01;(3R)-1-azabicyclo[2.2.2]octan-3-yl (1S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate hydrochloride;C23H26N2O2.ClH;CHEMBL2361425;DTXCID2026783;YAUBKMSXTZQZEB-VROPFNGYSA-N;HY-I0230;Tox21_112639;AKOS030241618;MS-26754;CAS-180468-39-7;A925289;EN300-19659453;EN300-22858780;(R)-Quinuclidin-3-yl (S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrochloride;(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride

Chemical Property of Solifenacin hydrochloride

Chemical Property:

• Vapor Pressure: 2.41E-10mmHg at 25°C
• Melting Point: 120-122°C
• Boiling Point: 505.5°Cat760mmHg
• Flash Point: 259.5°C
• PSA: 32.78000
• Density: g/cm³
• LogP: 4.54270
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility.: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 398.1761058
• Heavy Atom Count: 28
• Complexity: 525

Purity/Quality:

99% ^*data from raw suppliers

Solifenacin hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN2CCC1C(C2)OC(=O)N3CCC4=CC=CC=C4C3C5=CC=CC=C5.Cl
• Isomeric SMILES: C1CN2CCC1[C@H](C2)OC(=O)N3CCC4=CC=CC=C4[C@@H]3C5=CC=CC=C5.Cl
• Recent ClinicalTrials: Botulinum Toxin A vs Anticholinergic Treatment of Neurogenic Overactive Bladder in Patients With Multiple Sclerosis
• Recent EU Clinical Trials: PERIPHERAL TRANSCUTANEOUS NEUROMODULATION OF THE POST-TIBIAL NERVE (T-PTNS) FOR SOLIFENACIN 10mg. IN THE TREATMENT OF HYPERACTIVE BLADDER SYNDROME: NON-INFERIORITY PHASE IV RANDOMIZED CLINICAL TRIAL
• Uses: Solifenacin Hydrochloride can be used as muscarinic M3 receptor antagoinst and used in treatment of urinary incontinence Muscarinic M3 receptor antagoinst used in treatment of urinary incontinence.