Dimethyl dimethylphosphoramidate

Base Information

• Chemical Name: Dimethyl dimethylphosphoramidate
• CAS No.: 597-07-9
• Molecular Formula: C4H12NO3P
• Molecular Weight: 153.118
• Hs Code.: 2929903000
• European Community (EC) Number: 633-126-5
• DSSTox Substance ID: DTXSID20208405
• Nikkaji Number: J493.482B
• Wikidata: Q83082524
• Mol file: 597-07-9.mol

Synonyms:Dimethyl dimethylphosphoramidate;597-07-9;Dimethyl (dimethylamido)phosphate;Dimethylphosphoramidic acid dimethyl ester;Phosphoramidic acid, dimethyl-, dimethyl ester;1715 HC;BRN 1759752;4-04-00-00278 (Beilstein Handbook Reference);N-dimethoxyphosphoryl-N-methylmethanamine;dimethyldimethylamidophosphate;SCHEMBL400155;(CH3O)2PN(CH3)2;DTXSID20208405;Dimethyl N,N-dimethylphosphoroamidate;Dimethylphosporamidic acid dimethyl ester;LS-107329;FT-0718769

Chemical Property of Dimethyl dimethylphosphoramidate

Chemical Property:

• Vapor Pressure: 4.32mmHg at 25°C
• Boiling Point: 147.9°Cat760mmHg
• Flash Point: 43.3°C
• PSA: 48.58000
• Density: 1.104g/cm³
• LogP: 0.94890
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 153.05548024
• Heavy Atom Count: 9
• Complexity: 117

Purity/Quality:

97% ^*data from raw suppliers

DIMETHYL DIMETHYLPHOSPHORAMIDATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)P(=O)(OC)OC

Technology Process of Dimethyl dimethylphosphoramidate

There total 2 articles about Dimethyl dimethylphosphoramidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

N,N-dimethyl-benzothiazolesulphenamide (27464-39-7) + phosphorous acid trimethyl ester (121-45-9) → 2-methylmercaptobenzothiazole (615-22-5) + N,N-dimethyl-O,O-dimethylphosphoramidate (597-07-9)

Guidance literature:

In toluene; for 0.25h; Mechanism; Ambient temperature; further benzothiazol-2-yl sulphenamides, further phosphite (substituent effect);

Reference yield:

methyl phosphite (96-36-6,868-85-9) + dimethyl amine (124-40-3) → N,N-dimethyl-O,O-dimethylphosphoramidate (597-07-9)

Guidance literature:

With tetrachloromethane; benzene;

Reference yield:

N,N-dimethyl-O,O-dimethylphosphoramidate (597-07-9) + trifluorormethanesulfonic acid (1493-13-6) → dimethyl-amidophosphoric acid monomethyl ester (94274-60-9) + N,N-(dimethyl)-aminophosphonic acid (33876-51-6) + methyl trifluoromethanesulfonate (333-27-7)

Guidance literature:

Kinetics; Mechanism; further reagent: FSO₃H;

DOI:10.1039/c39800000201

upstream raw materials:

methyl phosphite

dimethyl amine

N,N-dimethyl-benzothiazolesulphenamide

phosphorous acid trimethyl ester

Downstream raw materials:

Phosphoric acid cyclohexyl dimethyl ester

dimethyl-amidophosphoric acid monomethyl ester

N,N-(dimethyl)-aminophosphonic acid

methyl trifluoromethanesulfonate

Refernces