3,5-Dichlorophenethyl broMide

Base Information

• Chemical Name: 3,5-Dichlorophenethyl broMide
• CAS No.: 93427-14-6
• Molecular Formula: C8H7BrCl2
• Molecular Weight: 253.954
• Mol file: 93427-14-6.mol

Synonyms:3,5-Dichlorophenethyl bromide;

Chemical Property of 3,5-Dichlorophenethyl broMide

Chemical Property:

• Boiling Point: 271.6±25.0 °C (760 mmHg)
• PSA: 0.00000
• Density: 1.593±0.06 g/cm3 (20 °C, 760 mmHg)
• LogP: 3.93080

Purity/Quality:

98% ^*data from raw suppliers

1-(2-Bromoethyl)-3,5-dichlorobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-Dichlorophenethyl broMide

There total 1 articles about 3,5-Dichlorophenethyl broMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3,5-Dichloro-β-phenethyl alcohol (93427-13-5) → C8H7BrCl2 (93427-14-6)

Guidance literature:

With 1H-imidazole; bromine; triphenylphosphine; In dichloromethane; at 20 ℃; for 0.5h;

Reference yield: 27.0%

C8H7BrCl2 (93427-14-6) + (R)-5-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one (128899-30-9,100548-49-0,106191-02-0) → C13H15Cl2NO2 (1145677-17-3)

Guidance literature:

(R)-5-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.75h;

C₈H₇BrCl₂; In N,N-dimethyl-formamide; at 50 ℃; for 18h;

With water; ammonium chloride; In N,N-dimethyl-formamide;

upstream raw materials:

3,5-Dichloro-β-phenethyl alcohol

Downstream raw materials:

C₁₃H₁₅Cl₂NO₂

Refernces