Hinokiol

Base Information Edit

Chemical Name:Hinokiol
CAS No.:564-73-8
Molecular Formula:C₂₀H₃₀O₂
Molecular Weight:302.457
Hs Code.:
ChEMBL ID:CHEMBL1277661
Metabolomics Workbench ID:123187
Nikkaji Number:J16.963C
Wikidata:Q104253844
Mol file:564-73-8.mol

Synonyms:hinokiol

Suppliers and Price of Hinokiol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
Hinokiol ≥98%
5mg
$ 456.00

Total 13 raw suppliers

Chemical Property of Hinokiol Edit

Chemical Property:

Vapor Pressure:4.71E-08mmHg at 25°C
Boiling Point:400.1°Cat760mmHg
Flash Point:184°C
PSA：40.46000
Density:1.107g/cm³
LogP:4.51660
XLogP3:5.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:302.224580195
Heavy Atom Count:22
Complexity:416

Purity/Quality:

99% ^*data from raw suppliers

Hinokiol ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=C(C=C2C(=C1)CCC3C2(CCC(C3(C)C)O)C)O
Isomeric SMILES:CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CC[C@@H](C3(C)C)O)C)O

Technology Process of Hinokiol

There total 15 articles about Hinokiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₁H₃₂O₂

: 33465-21-3,107740-34-1,564-73-8
hinokiol

: C₂₀H₃₀O₂

Guidance literature:: With magnesium; methyl iodide; In diethyl ether; at 160 ℃; for 2h; under 150 Torr; Overall yield = 85 %; Overall yield = 70.5 mg; Inert atmosphere; Schlenk technique;
DOI:10.1021/jacs.8b01660

Reference yield:

: 26804-77-3
abieta-5,6,11,13-tetraen-3-one

: 33465-21-3,107740-34-1,564-73-8
hinokiol

Guidance literature:: Multi-step reaction with 6 steps

1: 94.8 percent / LiAlH₄ / diethyl ether / 1.5 h / Ambient temperature

2: 67.3 percent / H₂ / 5percent Pd/C / methanol / 20 h / Ambient temperature

3: 96.3 percent / pyridine / 1.5 h / 74 - 77 °C

4: 95.3 percent / AlCl₃ / CH₂Cl₂ / a) 0-5 deg C, 30 min, b) RT, 24 h

5: 83.9 percent / m-chloroperbenzoic acid, p-toluenesulfonic acid / 1,2-dichloro-ethane / 3.5 h / Heating

6: LiAlH₄ / diethyl ether / a) 0-5 deg C, 45 min, b) RT, 30 min

With pyridine; lithium aluminium tetrahydride; aluminium trichloride; hydrogen; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; palladium on activated charcoal; In methanol; diethyl ether; dichloromethane; 1,2-dichloro-ethane;
DOI:10.1246/bcsj.54.581

Reference yield:

: 78078-40-7
abieta-5,8,11,13-tetraten-3β-ol

: 33465-21-3,107740-34-1,564-73-8
hinokiol

Guidance literature:: Multi-step reaction with 5 steps

1: 67.3 percent / H₂ / 5percent Pd/C / methanol / 20 h / Ambient temperature

2: 96.3 percent / pyridine / 1.5 h / 74 - 77 °C

3: 95.3 percent / AlCl₃ / CH₂Cl₂ / a) 0-5 deg C, 30 min, b) RT, 24 h

4: 83.9 percent / m-chloroperbenzoic acid, p-toluenesulfonic acid / 1,2-dichloro-ethane / 3.5 h / Heating

5: LiAlH₄ / diethyl ether / a) 0-5 deg C, 45 min, b) RT, 30 min

With pyridine; lithium aluminium tetrahydride; aluminium trichloride; hydrogen; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; palladium on activated charcoal; In methanol; diethyl ether; dichloromethane; 1,2-dichloro-ethane;
DOI:10.1246/bcsj.54.581