4-((1Z)-2-nitrovinyl)-1,2-dimethoxybenzene

Base Information

• Chemical Name: 4-((1Z)-2-nitrovinyl)-1,2-dimethoxybenzene
• CAS No.: 4230-93-7
• Molecular Formula: C10H11NO4
• Molecular Weight: 209.202
• Hs Code.: 2909309090
• NSC Number: 31600,7390
• Mol file: 4230-93-7.mol

Synonyms:4-((1Z)-2-nitrovinyl)-1,2-dimethoxybenzene;1,2-dimethoxy-4-[(Z)-2-nitroethenyl]benzene;NSC7390;NSC-7390;NSC31600;NSC-31600;AKOS002262998

Chemical Property of 4-((1Z)-2-nitrovinyl)-1,2-dimethoxybenzene

Chemical Property:

• Vapor Pressure: 0.000136mmHg at 25°C
• Melting Point: 140 °C
• Refractive Index: 1.564
• Boiling Point: 343.9 °C at 760 mmHg
• Flash Point: 158.6 °C
• PSA: 64.28000
• Density: 1.197 g/cm³
• LogP: 2.47440
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 209.06880783
• Heavy Atom Count: 15
• Complexity: 236

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,2-dimethoxy-4-(2-nitrovinyl)benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)C=C[N+](=O)[O-])OC
• Isomeric SMILES: COC1=C(C=C(C=C1)/C=C\[N+](=O)[O-])OC

Technology Process of 4-((1Z)-2-nitrovinyl)-1,2-dimethoxybenzene

There total 19 articles about 4-((1Z)-2-nitrovinyl)-1,2-dimethoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

nitromethane (75-52-5) + 3,4-dimethoxy-benzaldehyde (120-14-9) → 1,2-dimethoxy-4-(2-nitro-vinyl)-benzene (4230-93-7)

Guidance literature:

With ammonium acetate; In acetic acid; at 90 - 100 ℃; for 1h; Molecular sieve;

DOI:10.1055/s-0034-1379481

Reference yield: 93.0%

nitromethane (75-52-5) + 3,4-dimethoxy-benzaldehyde (120-14-9) → 3,4-dimethoxynitrostyrene (4230-93-7,22568-47-4)

Guidance literature:

With ethylenediamine; for 4h; Reagent/catalyst; Reflux;

DOI:10.1002/cjoc.201201094

Reference yield: 93.0%

→ 1,2-dimethoxy-4-(2-nitro-vinyl)-benzene (4230-93-7)

Guidance literature:

upstream raw materials:

nitromethane

3,4-dimethoxy-benzaldehyde

3,4-dimethoxy-trans-cinnamic acid

2-nitro-1-(3,4-dimethoxyphenyl)ethanol

Downstream raw materials:

(E)-1,2-dimethoxy-4-nitro-5-(2-nitroethenyl)benzene

4-(3,4-dimethyl-6-nitro-cyclohex-3-enyl)-1,2-dimethoxy-benzene

N-[1-(3,4-dimethoxy-phenyl)-2-nitro-ethyl]-N'-phenyl-hydrazine

4-{6-[1-(3,4-dimethoxy-phenyl)-2-nitro-ethyl]-cyclohex-1-enyl}-morpholine

Refernces

• 1、 Bai, Rongxian,Gao, Feng,Gu, Yanlong,Li, Minghao. "Dipolar HCP materials as alternatives to DMF solvent for azide-based synthesis". supporting information. p. 7499 - 7505. Retrieved 2021/10/12.
• 2、 Alves, Tania M. F.,Jardim, Guilherme A. M.,Ferreira, Marco A. B.. "A green metal-free "one-pot" microwave assisted synthesis of 1,4-dihydrochromene triazoles". . p. 10336 - 10339. Retrieved 2021/03/26.