Heptamethylcyclotetrasiloxane

Base Information

• Chemical Name: Heptamethylcyclotetrasiloxane
• CAS No.: 15721-05-8
• Molecular Formula: C7H22O4Si4
• Molecular Weight: 282.591
• Hs Code.: 2901100000
• European Community (EC) Number: 688-328-6
• DSSTox Substance ID: DTXSID10166227
• Wikidata: Q83035451
• Mol file: 15721-05-8.mol

Synonyms:Heptamethylcyclotetrasiloxane;15721-05-8;HEPTAMETHYL CYCLOTETRASILOXANE;CYCLOTETRASILOXANE, HEPTAMETHYL-;BRN 1786647;Cyclotetrasiloxane, 2,2,4,4,6,6,8-heptamethyl-;C7H22O4Si4;SCHEMBL116238;C7-H22-O4-Si4;DTXSID10166227;MFCD00040367;LS-58849;FT-0768915;Cyclotetrasiloxane,2,2,4,4,6,6,8-heptamethyl-;2,2,4,4,6,6,8-heptamethyl-1,3,5,7,2,4,6,8$l^{3};2,2,4,4,6,6,8-heptamethyl-1,3,5,7,2,4,6,8lambda3-tetraoxatetrasilocane

Chemical Property of Heptamethylcyclotetrasiloxane

Chemical Property:

• Melting Point: -27 °C
• Refractive Index: 1.3965
• Boiling Point: 174.3 °C at 760 mmHg
• Flash Point: 59.2 °C
• PSA: 36.92000
• Density: 0,958 g/cm3
• LogP: 2.02210
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 281.05169028
• Heavy Atom Count: 15
• Complexity: 221

Purity/Quality:

98%,99%, ^*data from raw suppliers

Heptamethylcyclotetrasiloxane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R10:
• Hazard Codes: R10:
• Statements: 10
• Safety Statements: 16

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si]1O[Si](O[Si](O[Si](O1)(C)C)(C)C)(C)C
• Uses: Heptamethylcyclotetrasiloxane is used in the study of the structure-activity relations of organosiloxanes and the female reproductive system.

Technology Process of Heptamethylcyclotetrasiloxane

There total 5 articles about Heptamethylcyclotetrasiloxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

Dichloromethylsilane (75-54-7) + dimethylsilicon dichloride (75-78-5,30107-43-8) → 1,3,3,5,5,7,7-heptamethyl-1,3,5,7-cyclotetrasiloxane (15721-05-8)

Guidance literature:

In diethyl ether; water; at 0 - 5 ℃; for 1h;

Reference yield: 5.0%

Dichloromethylsilane (75-54-7) + 1,5-dichlorohexamethyltrisiloxane (3582-71-6) → 1,3,3,5,5,7,7-heptamethyl-1,3,5,7-cyclotetrasiloxane (15721-05-8)

Guidance literature:

triethylamine; In tetrahydrofuran; water; for 5h; in dry-ice aceton bath;

DOI:10.1016/S0022-328X(00)99534-2

Reference yield:

benzyl dimethylsilyl ether (2487-89-0) → Hexamethylcyclotrisiloxane (541-05-9) + 1,3,3,5,5,7,7-heptamethyl-1,3,5,7-cyclotetrasiloxane (15721-05-8) + octamethylcyclotetrasiloxane (556-67-2) + ethylbenzene (100-41-4,27536-89-6) + toluene (108-88-3,15644-74-3,16713-13-6) + pentamethylcyclotrisiloxane

Guidance literature:

at 630 ℃; Product distribution;

upstream raw materials:

Dichloromethylsilane

dimethylsilicon dichloride

benzyl dimethylsilyl ether

1,5-dichlorohexamethyltrisiloxane

Downstream raw materials:

tetradecamethyl-[2,2']bi[cyclotetrasiloxanyl]

2-pentene

Heptamethyl-<2-phenyl-propyl>-cyclotetrasiloxan

2-chloro-2,4,4,6,6,8,8-heptamethylcyclotetrasiloxane

Refernces

• 1、 Makarova,Astapova,Lavrukhin. "Synthesis of organosiloxanes with reactive groups at silicon atoms". . p. 914 - 919. Retrieved 2007/10/03.
• 2、 Juengst, Clifford D.,Weber, William P.,Manuel, Georges. "SYNTHESIS OF SPIROCYCLOSILOXANES BY FLASH VACUUM PYROLYSIS OF 2,7-DIMETHYL-2,3:7,8-DIEPOXY-5-SILASPIRONONANE AND CYCLOSILOXANES". . p. 187 - 194. Retrieved 2007/10/02.