Cocamidopropyl betaine

Base Information

• Chemical Name: Cocamidopropyl betaine
• CAS No.: 4292-10-8
• Deprecated CAS: 5437-10-5,65277-51-2,1616934-80-5,86243-76-7,1616934-80-5
• Molecular Formula: C₁₉H₃₈N₂O₃
• Molecular Weight: 342.522
• Hs Code.: 2923.90 DERIVATION
• European Community (EC) Number: 224-292-6,263-058-8,617-822-6,617-861-9,687-442-3
• NSC Number: 8191
• UNII: 23D6XVI233
• DSSTox Substance ID: DTXSID4041282
• Wikipedia: Cocamidopropyl_betaine
• Wikidata: Q1090054
• NCI Thesaurus Code: C83635,C83865
• RXCUI: 1311186,1311576,2263872
• ChEMBL ID: CHEMBL1231297
• Mol file: 4292-10-8.mol

Synonyms:cocamidopropyl betaine;cocamidopropylbetaine

Chemical Property of Cocamidopropyl betaine

Chemical Property:

• Appearance/Colour: Clear to pale yellow liquid
• Vapor Pressure: 0.31Pa at 20℃
• Melting Point: -3oC
• Boiling Point: 100oC
• Flash Point: 94oC
• PSA: 89.46000
• Density: 1.15[at 20℃]
• LogP: 3.78870
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• Water Solubility.: 250mg/L at 20℃
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 15
• Exact Mass: 342.28824308
• Heavy Atom Count: 24
• Complexity: 338

Purity/Quality:

99% ^*data from raw suppliers

Lauroylamide Propylbetaine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Chemical Classes: Other Uses -> Emulsifiers/Surfactants
• Canonical SMILES: CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(=O)[O-]
• Description: Lauramidopropyl betaine is a new type of special amphoteric surfactant, which belongs to the same series as lauramidopropyl betaine, and is a modified derivative of alkyl betaine. Lauramidopropyl betaine has the characteristics of temperature resistance, acid and alkali resistance, good salt resistance, wide isoelectric point and strong viscoelasticity, etc. It is widely used in oil field oil repelling, leather, daily chemical industry and other fields. As a good viscoelastic surfactant applied to the substrate acidification of oilfield, it can effectively reduce the oil/water interfacial tension and improve the recovery rate of tertiary oil recovery. Also it can be used as conditioning agent, wetting agent, bactericide, antistatic agent, emulsifier, thickener and in self-steering acid system for carbonate acidification.
• Uses: Lauroylamide Propylbetaine is used cosmetic and hair compositions of enhanced viscosity and clarity.

Technology Process of Cocamidopropyl betaine

There total 3 articles about Cocamidopropyl betaine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

lauric acid dimethylaminopropylamide (3179-80-4) + sodium monochloroacetic acid (3926-62-3) → Cocamidopropyl betaine (4292-10-8,65277-51-2)

Guidance literature:

With sodium hydroxide; In water; at 98 ℃; for 5h; pH=7.5;

Reference yield:

lauric acid dimethylaminopropylamide (3179-80-4) + chloroacetic acid (79-11-8) → Cocamidopropyl betaine (4292-10-8,65277-51-2)

Guidance literature:

With sodium hydroxide; In water; at 80 - 105 ℃; for 9h; pH=8.5 - 12;

Reference yield:

lauric acid (143-07-7) + 1-amino-3-(dimethylamino)propane (109-55-7) → Cocamidopropyl betaine (4292-10-8,65277-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium tetrahydroborate / 100 °C / Inert atmosphere

1.2: 7 h / 160 - 170 °C

2.1: sodium hydroxide / water / 9 h / 80 - 105 °C / pH 8.5 - 12

With sodium tetrahydroborate; sodium hydroxide; In water;

upstream raw materials:

lauric acid dimethylaminopropylamide

sodium monochloroacetic acid

lauric acid

1-amino-3-(dimethylamino)propane

Refernces

• 1、 -. "Compounds and Relative use for the Control of Phytopathogens". Page/Page column 7. . Retrieved 2009/05/29.