7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid

Base Information

• Chemical Name: 7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid
• CAS No.: 493-90-3
• Molecular Formula: C34H38N4O4
• Molecular Weight: 566.7
• Mol file: 493-90-3.mol

Synonyms:2,4-diethyldeuteroporphyrin;2,4-Diethylbenzenamine;2,4-dimethylmethylaniline;Mesoporphyrin;2,4-diethyl-aniline;4-Amino-1.3-diaethyl-benzol;Mesoporphyrin IX;7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid;2,4-Diethylanilin;2,4-diethyl-1-aminobenzene;Benzenamine,2,4-diethyl;2,4-Diaethyl-anilin;

Chemical Property of 7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid

Chemical Property:

• Melting Point: >270oC
• Boiling Point: 1109.7°Cat760mmHg
• Flash Point: 624.9°C
• PSA: 130.90000
• Density: 1.24g/cm³
• LogP: 5.78800

Purity/Quality:

99% ^*data from raw suppliers

Mesoporphyrin IX - reference standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Mesoporphyrin IX is used in preparation method, application of ultrasonic deformation material.

Technology Process of 7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid

There total 13 articles about 7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 2.0%

mesoporphyrin IX methylene diester → 3,8-diethyl-13,17-di(1-hydroxypropan-3-yl)-2,7,12,18-tetramethylporphyrin (10199-94-7) + mesoporphyrin IX-7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphyrin-2,18-dipropionic acid (493-90-3) + 3,8-diethyl-17-(3-hydroxypropan-1-yl)-13-(2-carboxyethyl)-2,7,12,18-tetramethylporphyrin + 3,8-diethyl-13-(3-hydroxypropan-1-yl)-17-(2-carboxyethyl)-2,7,12,18-tetramethylporphyrin

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; at 65 ℃; for 6h; Title compound not separated from byproducts;

DOI:10.1080/00397919708004080

Reference yield:

hemin → mesoporphyrin IX (493-90-3)

Guidance literature:

With potassium hydroxide; palladium on activated charcoal; Hydrogenation;

DOI:10.1021/ja01859a504

Reference yield:

haematoporphyrin dibenzyl ester diacetate (75162-75-3) → mesoporphyrin IX (493-90-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran;

upstream raw materials:

protoporphyrin IX

21H,23H-porphine-2,18-dipropanoicacid,7,12-diethenyl-3,8,13,17-tetramethyl-, 2,18-diethyl ester

3,3'-(3,7,12,17-tetramethyl-8,13-divinyl-21H,23H-porphine-2,18-diyl)-bis-propionic acid dimethyl ester

ascorbic acid

Downstream raw materials:

3-ethyl-4-methyl-pyrrole-2,5-dione

2,4-dimethyl-3-pyrrolepropanoic acid

3-(4,5-dimethyl-pyrrol-3-yl)-propionic acid

2-propionic-3-methylmaleic anhydride

Refernces

• 1、 Benitez, Pilar,Delgado, Ana,Farrera, Joan-Anton,Ribo, Josep M.. "Preparation of ω-hydroxy acids by reduction of α,ω-methylene diesters with NaBH4". . p. 1697 - 1702. Retrieved 2007/10/03.