1,1-dibromo-2,2-dimethylcyclopropane

Base Information

• Chemical Name: 1,1-dibromo-2,2-dimethylcyclopropane
• CAS No.: 32264-50-9
• Molecular Formula: C5H8 Br2
• Molecular Weight: 227.927
• Mol file: 32264-50-9.mol

Synonyms:1,1-Dibromo-2,2-dimethylcyclopropane;NSC 288505

Chemical Property of 1,1-dibromo-2,2-dimethylcyclopropane

Chemical Property:

• Vapor Pressure: 4.08mmHg at 25°C
• Boiling Point: 154.5°Cat760mmHg
• Flash Point: 34.6°C
• Density: 1.918g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,1-dibromo-2,2-dimethylcyclopropane

There total 8 articles about 1,1-dibromo-2,2-dimethylcyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Bromoform (75-25-2) + isobutene (115-11-7,15220-85-6) → 1,1-dibromo-2,2-dimethylcyclopropane (32264-50-9)

Guidance literature:

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In ethanol; dichloromethane; for 5h;

DOI:10.1055/s-1982-29786

Reference yield: 95.0%

3,3-dimethyl-1,1,2,2-tetrabromocyclopropane (99236-10-9) → 1,1-dibromo-2,2-dimethylcyclopropane (32264-50-9) + 1,1,3‐tribromo‐2,2‐dimethylcyclopropane (23534-97-6)

Guidance literature:

With titanium(IV) isopropylate; ethylmagnesium bromide; In diethyl ether; at 20 ℃; for 0.166667h;

Reference yield:

2,3-Dimethyl-2-butene (563-79-1) + dibromocarbene (135226-15-2,4371-77-1) → 1,1-dibromo-2,2-dimethylcyclopropane (32264-50-9) + 2,2,3,3-tetramethyl-1,1-dibromocyclopropane (22715-57-7)

Guidance literature:

at -3.1 - 146.9 ℃; Product distribution; competitive edukt: 2-methyl-prop-1-en, various temp., influence of variation of reactants (further subst. ethenes) to isoselective temp.;

upstream raw materials:

Bromoform

isobutene

1-penten

2,3-Dimethyl-2-butene

Downstream raw materials:

(S)-N-(2-bromo-3-methyl-2-butenyl)-1-phenylethylamine

2,2-dibromo-1-methylcyclopropanecarboxylic acid

N-(2-bromo-3-methyl-2-butenyl)-cyclohexylamine

6,6-Dimethyl-4-phenyl-2-oxa-3-aza-bicyclo[3.1.0]hex-3-ene

Refernces

• 1、 Lilje,Macomber. "". . p. 3600. Retrieved 1974.
• 2、 Nefedov et al.. "-". . . Retrieved 1979.
• 3、 Müller, Daniel S.,Werner, Veronika,Akyol, Sema,Schmalz, Hans-Günther,Marek, Ilan. "Tandem Hydroalumination/Cu-Catalyzed Asymmetric Vinyl Metalation as a New Access to Enantioenriched Vinylcyclopropane Derivatives". supporting information. p. 3970 - 3973. Retrieved 2017/08/14.
• 4、 Dulayymi, Juma'a R. Al,Baird, Mark S.,Bolesov, Ivan G.,Nizovtsev, Alexey V.,Tverezovsky, Viacheslav V.. "Hydrodehalogenation of 1,1-dibromocyclopropanes by Grignard reagents promoted by titanium compounds". . p. 1603 - 1618. Retrieved 2007/10/03.