Methyl cyclopentylideneacetate

Base Information

• Chemical Name: Methyl cyclopentylideneacetate
• CAS No.: 40203-73-4
• Molecular Formula: C8H12O2
• Molecular Weight: 140.182
• Hs Code.: 2916209090
• European Community (EC) Number: 254-837-3
• DSSTox Substance ID: DTXSID2052077
• Nikkaji Number: J23.238F
• Mol file: 40203-73-4.mol

Synonyms:40203-73-4;Methyl cyclopentylideneacetate;methyl 2-cyclopentylideneacetate;CYCLOPENTYLIDENEACETIC ACID METHYL ESTER;Cyclopentylidene-acetic acid methyl ester;Cyclopentylideneacetic acid, methyl ester;Acetic acid, cyclopentylidene-, methyl ester;Acetic acid, 2-cyclopentylidene-, methyl ester;EINECS 254-837-3;EC 254-837-3;cyclopidene;Cyclopentylideneaceticacidmethylester;methyl2-cyclopentylideneacetate;SCHEMBL873013;DTXSID2052077;AKOS017417055;BS-28158;AM20100069;CS-0218025;FT-0624272;EN300-97942

Chemical Property of Methyl cyclopentylideneacetate

Chemical Property:

• Vapor Pressure: 0.458mmHg at 25°C
• Boiling Point: 193.7°Cat760mmHg
• Flash Point: 90.3°C
• PSA: 26.30000
• Density: 1.113g/cm³
• LogP: 1.65980
• Water Solubility.: 1.53g/L at 20℃
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 140.083729621
• Heavy Atom Count: 10
• Complexity: 151

Purity/Quality:

99.9% ^*data from raw suppliers

Cyclopentylidene-acetic acid methyl ester 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C=C1CCCC1

Technology Process of Methyl cyclopentylideneacetate

There total 19 articles about Methyl cyclopentylideneacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Cyclopentenyl-1-acetic acid methyl ester (21622-07-1) → Cyclopentylideneacetic acid methyl ester (40203-73-4)

Guidance literature:

With potassium hydrogensulfate; at 160 ℃; for 2h;

DOI:10.1021/jo00216a015

Reference yield: 98.0%

trimethyl phosphonoacetate (5927-18-4) + cyclopentanone (120-92-3) → Cyclopentylideneacetic acid methyl ester (40203-73-4)

Guidance literature:

DOI:10.1016/S0040-4039(00)73448-4

Reference yield: 92.0%

phosphonoacetic acid (4408-78-0) + cyclopentanone (120-92-3) → Cyclopentylideneacetic acid methyl ester (40203-73-4)

Guidance literature:

In N,N,N,N,N,N-hexamethylphosphoric triamide; di-isopropyl ether;

upstream raw materials:

Cyclopentenyl-1-acetic acid methyl ester

sodium methylate

trimethyl phosphonoacetate

cyclopentanone

Downstream raw materials:

1-benzyl-1-oxo-2-phenyl-1λ⁵-phospha-spiro[4.4]nonan-3-one

1-oxo-1,2-diphenyl-1λ⁵-phospha-spiro[4.4]nonan-3-one

ethyl cyclopentylideneacetate

Cyclopent-1-enyl-(1-hydroxy-cyclohexyl)-acetic acid methyl ester

Refernces

• 1、 Hirano, Koji,Miura, Masahiro,Xu, Shibo. "Pd-catalyzed regioselective C?H alkenylation and alkynylation of allylic alcohols with the assistance of a bidentate phenanthroline auxiliary". supporting information. p. 9059 - 9064. Retrieved 2020/12/02.
• 2、 Brimioulle, Richard,Bach, Thorsten. "Photocycloaddition of 3-alkenyloxy-2-cycloalkenones: Enantioselective lewis acid catalysis and ring expansion". supporting information. p. 12921 - 12924. Retrieved 2016/02/18.