Cloprednol

Base Information

• Chemical Name: Cloprednol
• CAS No.: 5251-34-3
• Molecular Formula: C21H25ClO5
• Molecular Weight: 392.88
• European Community (EC) Number: 226-052-6
• UNII: SYP56O3GJG
• DSSTox Substance ID: DTXSID1022849
• Nikkaji Number: J8.826I
• Wikipedia: Cloprednol
• Wikidata: Q3680915
• NCI Thesaurus Code: C80809
• Metabolomics Workbench ID: 154621
• ChEMBL ID: CHEMBL1697832
• Mol file: 5251-34-3.mol

Synonyms:cloprednol

Chemical Property of Cloprednol

Chemical Property:

• Vapor Pressure: 6.47E-17mmHg at 25°C
• Refractive Index: 1.635
• Boiling Point: 600.3 °C at 760 mmHg
• PKA: 12.30±0.70(Predicted)
• Flash Point: 316.9 °C
• PSA: 94.83000
• Density: 1.4 g/cm³
• LogP: 1.90010
• Storage Temp.: -20°C Freezer
• Solubility.: Ethyl Acetate (Slightly), Methanol (Slightly)
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 392.1390516
• Heavy Atom Count: 27
• Complexity: 813

Purity/Quality:

95-99% ^*data from raw suppliers

Cloprednol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CC(C3C(C1CCC2(C(=O)CO)O)C=C(C4=CC(=O)C=CC34C)Cl)O
• Isomeric SMILES: C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)C=C(C4=CC(=O)C=C[C@]34C)Cl)O
• Uses: A systematic corticosteroid. Anti-inflammatory.
• Therapeutic Function: Glucocorticoid

Technology Process of Cloprednol

There total 1 articles about Cloprednol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 6-chloro-11β,17α,21-trihydroxypregna-1,4,6-triene-3,20-dione (5251-34-3)

Guidance literature:

Refernces