Forchlorfenuron

Base Information

• Chemical Name: Forchlorfenuron
• CAS No.: 68157-60-8
• Molecular Formula: C12H10ClN3O
• Molecular Weight: 247.684
• Hs Code.: 29333990
• European Community (EC) Number: 614-346-0
• UNII: K62IP7463J
• DSSTox Substance ID: DTXSID1034634
• Nikkaji Number: J236.162K
• Wikipedia: Forchlorfenuron
• Wikidata: Q408770
• ChEMBL ID: CHEMBL1229826
• Mol file: 68157-60-8.mol

Synonyms:4PU30 cpd;forchlorfenuron;N-(2-chloro-4-pyridyl)-N'-phenylurea

Chemical Property of Forchlorfenuron

Chemical Property:

• Appearance/Colour: white crystals
• Melting Point: 170-172 °C
• Boiling Point: 308.418 °C at 760 mmHg
• PKA: 12.55±0.70(Predicted)
• Flash Point: 140.326 °C
• PSA: 54.02000
• Density: 1.415 g/cm³
• LogP: 3.52500
• Storage Temp.: 2-8°C
• Solubility.: Soluble in DMSO or Ethanol
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 247.0512396
• Heavy Atom Count: 17
• Complexity: 256

Purity/Quality:

99% ^*data from raw suppliers

Forchlorfenuron ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,N,Xn
• Statements: 36/37-51/53-40
• Safety Statements: 26-36-61-46-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NC(=O)NC2=CC(=NC=C2)Cl
• Description: Forchlorfenuron (68157-60-8) reversibly perturbs mammalian septin assembly, organization and function.? Has no effect on actin or tubulin polymerization.1,2 FCF induces effects on mitosis and migration which phenocopy the effects induced by septin depletion using siRNA.1 A useful tool for exploring the physiological role of septin and its complexes.3,4
• Uses: Forchlorfenuronis is a diphenylurea-derivative cytokinin. Forchlorfenuronis is used as a plant growth regulator (PGR). Forchlorfenuronis is commonly used in horticulture to stimulate the growth of kiw i fruit and grapes.

Technology Process of Forchlorfenuron

There total 2 articles about Forchlorfenuron which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2,4-dichloropyridine (26452-80-2) + phenyl carbamate (64-10-8) → N-(4-chloropyridin-2-yl)-N'-phenylurea + N-(2-chloro-4-pyridyl)-N'-phenylurea (68157-60-8)

Guidance literature:

With 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium t-butanolate; palladium diacetate; In 1,4-dioxane; at 100 ℃; for 3.5h;

DOI:10.1055/s-2005-861844

Reference yield:

→ N-(2-chloro-4-pyridyl)-N'-phenylurea (68157-60-8)

Guidance literature:

entspr. Phenylisocyanat, 2-Chlor-4-amino-pyridin;

DOI:10.1016/S0031-9422(00)94556-4

Reference yield:

N-(2-chloro-4-pyridyl)-N'-phenylurea (68157-60-8) → 4-Amino-2-chloropyridine (14432-12-3) + methanol (67-56-1) + aniline (62-53-3)

Guidance literature:

With C₃₀H₂₉BrMnNO₂P₂; potassium tert-butylate; In isopropyl alcohol; toluene; at 120 ℃; for 16h;

DOI:10.1039/d1sc02663a

upstream raw materials:

2,4-dichloropyridine

phenyl carbamate

Downstream raw materials:

4-Amino-2-chloropyridine

methanol

aniline

Refernces

• 1、 -. "Patch preparations for treating plants". . . Retrieved 2008/06/13.