4-METHOXY-3-PROPOXYBENZALDEHYDE

Base Information

• Chemical Name: 4-METHOXY-3-PROPOXYBENZALDEHYDE
• CAS No.: 5922-56-5
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Hs Code.: 2912499000
• Mol file: 5922-56-5.mol

Synonyms:Benzaldehyde,4-methoxy-3-propoxy;3-n-propoxy-4-methoxybenzaldehyde;4-methoxy-3-n-propoxybenzaldehyde;4-Methoxy-3-propoxy-benzaldehyd;4-methoxy-3-propoxy-benzaldehyde;

Chemical Property of 4-METHOXY-3-PROPOXYBENZALDEHYDE

Chemical Property:

• Vapor Pressure: 3.82E-16mmHg at 25°C
• Boiling Point: 637.4°C at 760 mmHg
• Flash Point: 339.3°C
• PSA: 35.53000
• Density: 1.392g/cm³
• LogP: 2.29650

Purity/Quality:

98%min ^*data from raw suppliers

4-Methoxy-3-propoxybenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-METHOXY-3-PROPOXYBENZALDEHYDE

There total 9 articles about 4-METHOXY-3-PROPOXYBENZALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

isovanillin (621-59-0) + 1-iodo-propane (107-08-4) → 4-methoxy-3-propoxy-benzaldehyde (5922-56-5)

Guidance literature:

With potassium carbonate; potassium iodide; In butanone; Reflux;

Reference yield: 96.0%

4-hydroxy-3-propoxybenzaldehyde (110943-74-3) + dimethyl sulfate (77-78-1) → 4-methoxy-3-propoxy-benzaldehyde (5922-56-5)

Guidance literature:

With sodium hydroxide; In water; at 90 ℃; for 2.66667h; Inert atmosphere;

DOI:10.1002/ejoc.201500500

Reference yield: 74.0%

isovanillin (621-59-0) + propyl bromide (106-94-5) → 4-methoxy-3-propoxy-benzaldehyde (5922-56-5)

Guidance literature:

isovanillin; In N,N-dimethyl-formamide; for 0.166667h; Reflux; Alkaline conditions;

propyl bromide; In N,N-dimethyl-formamide; for 5h; Reflux;

DOI:10.1016/j.bioorg.2018.10.029

upstream raw materials:

isovanillin

propyl bromide

3-(3-bromopropoxy)-4-methoxybenzaldehyde

1-iodo-propane

Downstream raw materials:

4-Methoxy-3-propoxy-benzoic acid

(E)-3-(4-Methoxy-3-propoxy-phenyl)-thioacrylamide

3-(propyloxy)-4-methoxybenzyl alcohol

isovanillin

Refernces

• 1、 -. "Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection". Paragraph 1110; 1111. . Retrieved 2015/08/04.
• 2、 -. "PERFUME SYSTEMS". Page/Page column 67. . Retrieved 2015/12/08.