1,2-Bis(2-methylphenyl)hydrazine

Base Information

• Chemical Name: 1,2-Bis(2-methylphenyl)hydrazine
• CAS No.: 617-22-1
• Molecular Formula: C14H16N2
• Molecular Weight: 212.294
• Hs Code.: 2928000090
• NSC Number: 309
• UNII: TOV0T72NDE
• DSSTox Substance ID: DTXSID2060672
• Nikkaji Number: J94.893D
• Wikidata: Q81989152
• Mol file: 617-22-1.mol

Synonyms:1,2-Bis(2-methylphenyl)hydrazine;1,2-Di-o-tolylhydrazine;617-22-1;o,o'-Hydrazotoluene;2,2'-Dimethylhydrazobenzene;Hydrazine, 1,2-bis(2-methylphenyl)-;o-Hydrazotoluene;Hydrazine, 1,2-di-o-tolyl-;TOV0T72NDE;NSC 309;NSC-309;Hydrazotoluol;NSC309;UNII-TOV0T72NDE;Hydrazine,2-di-o-tolyl-;1,2-bis(o-tolyl)-hydrazine;SCHEMBL9355162;DTXSID2060672;Hydrazine,2-bis(2-methylphenyl)-;AKOS024332611

Chemical Property of 1,2-Bis(2-methylphenyl)hydrazine

Chemical Property:

• Vapor Pressure: 0.0133mmHg at 25°C
• Boiling Point: 259°Cat760mmHg
• Flash Point: 105.3°C
• PSA: 24.06000
• Density: 1.124g/cm³
• LogP: 3.98010
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 212.131348519
• Heavy Atom Count: 16
• Complexity: 183

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1NNC2=CC=CC=C2C

Technology Process of 1,2-Bis(2-methylphenyl)hydrazine

There total 22 articles about 1,2-Bis(2-methylphenyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.2%

1-methyl-2-nitrobenzene (88-72-2) → 2,2'-dimethylhydrazobenzene (617-22-1)

Guidance literature:

With 0.8wt% Pd/C; hydrogen; sodium dodecylbenzenesulfonate; sodium hydroxide; [1,4]naphthoquinone; In ethanol; at 30 ℃; under 4500.45 Torr; Autoclave;

Reference yield: 90.0%

trans-di-o-tolyl-diazene (584-90-7) → 2,2'-dimethylhydrazobenzene (617-22-1)

Guidance literature:

With borane-ammonia complex; tris(quinolin-8-yl)phosphite; In tetrahydrofuran; at 60 ℃; for 24h; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1002/ejic.201900572

Reference yield: 90.0%

N,N'-Di-o-tolyl-diazene N-oxide (956-31-0,51284-68-5,116723-89-8) → 2,2'-dimethylhydrazobenzene (617-22-1)

Guidance literature:

With hydrazine hydrate; aluminium; In methanol; for 1.75h; microwave irradiation;

DOI:10.1080/00397910500182275

upstream raw materials:

1-methyl-2-nitrobenzene

chlorobenzene

2,2'-dimethylazobenzene

N,N'-Di-o-tolyl-diazene N-oxide

Downstream raw materials:

N,N-di-o-tolylthiourea

2,2'-dimethylazobenzene

o-toluidine

o-tolidin

Refernces

• 1、 Song, Menghui,Zhou, Hongyan,Wang, Ganggang,Ma, Ben,Jiang, Yajing,Yang, Jingya,Huo, Congde,Wang, Xi-Cun. "Visible-Light-Promoted Diboron-Mediated Transfer Hydrogenation of Azobenzenes to Hydrazobenzenes". . p. 4804 - 4811. Retrieved 2021/04/06.
• 2、 Yan, Ziqiang,Xie, Xiaoyu,Song, Qun,Ma, Fulei,Sui, Xinyu,Huo, Ziyu,Ma, Mingming. "Tandem selective reduction of nitroarenes catalyzed by palladium nanoclusters". supporting information. p. 1301 - 1307. Retrieved 2020/03/11.