CID 556230

Base Information

• Chemical Name: CID 556230
• CAS No.: 1126-58-5
• Molecular Formula: C7H10N3O.Cl
• Molecular Weight: 187.629
• Hs Code.: 29333990
• Mol file: 1126-58-5.mol

Synonyms:

Chemical Property of CID 556230

Chemical Property:

• Appearance/Colour: Clear brown-yellow to brown-red liquid
• Melting Point: 201-203 °C
• PSA: 59.00000
• LogP: -2.94080
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Sparingly, Heated), Methanol (Slightly)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 187.0512396
• Heavy Atom Count: 12
• Complexity: 137

Purity/Quality:

99% ^*data from raw suppliers

Girard's Reagent P ^*data from reagent suppliers

Safty Information:

• Statements: 36/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=[N+](C=C1)CC(=O)NN.[Cl-]
• Uses: Girard’s reagent used in the identification and quantification of protein carbonylation as well as in the modification of nucleosides and nucleotides. Used in the preparation of potent photoactive agents. GIRARD'S REAGENT P used in the identification and quantification of protein carbonylation as well as in the modification of nucleosides and nucleotides. Used in the preparation of potent photoactive agents.

Technology Process of CID 556230

There total 4 articles about CID 556230 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[benz-(E)-ylidenehydrazinecarbonylmethyl]pyridinium chloride → girard's reagent P (1126-58-5) + benzaldehyde (100-52-7)

Guidance literature:

With water; In ethanol; pH=2.47; Rate constant; Phosphoric acid buffer;

Reference yield:

1-(2-oxo-2-{(2E)-2-[(2E)-3-phenyl-2-propenylidene]hydrazino}ethyl)-pyridinium chloride → (E)-3-phenylpropenal (14371-10-9) + girard's reagent P (1126-58-5)

Guidance literature:

With water; In ethanol; pH=4.48; Rate constant; Citric acid buffer;

Reference yield:

pyridine (110-86-1) + chloroacetic acid ethyl ester (105-39-5) → girard's reagent P (1126-58-5)

Guidance literature:

With ethanol; anschliessend Erwaermen mit Hydrazin-hydrat;

DOI:10.1002/hlca.193601901148

upstream raw materials:

pyridine

chloroacetic acid ethyl ester

Downstream raw materials:

GRP-retinal

N-<2-(p-nitrobenzylidene)hydrazinocarbonylmethyl>pyridinium chloride

N-{[(phenylamino) thioxomethyl] hydrazinocarbonylmethyl}pyridinium chloride

1-{2-[2-benzylidenehydrazino]-2-oxoethyl}pyridinium chloride

Refernces

• 1、 Levrand, Barbara,Fieber, Wolfgang,Lehn, Jean-Marie,Herrmann, Andreas. "Controlled release of volatile aldehydes and ketones from dynamic mixtures generated by reversible hydrazone formation". . p. 2281 - 2314. Retrieved 2008/03/29.