Benzeneethanamine, N-(diphenylmethyl)-

Base Information

• Chemical Name: Benzeneethanamine, N-(diphenylmethyl)-
• CAS No.: 97780-85-3
• Molecular Formula: C21H21N
• Molecular Weight: 287.404
• Mol file: 97780-85-3.mol

Synonyms:

Chemical Property of Benzeneethanamine, N-(diphenylmethyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzeneethanamine, N-(diphenylmethyl)-

There total 9 articles about Benzeneethanamine, N-(diphenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

1-phenyl-2-bromoethane (103-63-9) + Benzhydrylamine (91-00-9) → N-benzhydryl-2-phenylethan-1-amine (97780-85-3)

Guidance literature:

With potassium carbonate; In acetonitrile; at 100 ℃; for 12h; Inert atmosphere;

DOI:10.1021/jacs.0c13200

Reference yield: 64.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + Benzhydrylamine (91-00-9) → (1,1,3-triphenylpropyl)amine + N-benzhydryl-2-phenylethan-1-amine (97780-85-3)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; lithium hexamethyldisilazane; In benzene-d6; at 120 ℃; for 19h;

DOI:10.1002/ejoc.200700147

Reference yield:

2-phenylethyl tosylate (4455-09-8) + Benzhydrylamine (91-00-9) → N-benzhydryl-2-phenylethan-1-amine (97780-85-3)

Guidance literature:

With sodium carbonate; In acetonitrile; at 70 ℃;

DOI:10.3184/174751918X15232662638058

upstream raw materials:

N-(diphenylmethylidene)-N-(2-phenylethyl)amine

phenethylamine

Bromodiphenylmethane

styrene

Downstream raw materials:

1,1-Diphenylmethanol

phenethylamine

N-(diphenylmethylidene)-N-(2-phenylethyl)amine

Refernces

• 1、 Sun, Quan-Wei,Xing, Jun-De,Qin, Yu-Hong,Yin, Xu-Wen,Zhou, Yi. "Benzhydrylamine: An effective aminating agent for the synthesis of primary amines". . p. 181 - 183. Retrieved 2018/05/26.
• 2、 Horrillo-Martinez, Patricia,Hultzsch, Kai C.,Gil, Adria,Branchadell, Vicenc. "Base-catalyzed anti-Markovnikov hydroamination of vinylarenes - Scope, limitations and computational studies". . p. 3311 - 3325. Retrieved 2008/02/10.