L-Proline, 5-oxo-1-(phenylacetyl)-, trimethylsilyl ester

Base Information

• Chemical Name: L-Proline, 5-oxo-1-(phenylacetyl)-, trimethylsilyl ester
• CAS No.: 98062-32-9
• Molecular Formula: C16H21NO4Si
• Molecular Weight: 319.433
• Mol file: 98062-32-9.mol

Synonyms:L-Proline, 5-oxo-1-(phenylacetyl)-, trimethylsilyl ester

Chemical Property of L-Proline, 5-oxo-1-(phenylacetyl)-, trimethylsilyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of L-Proline, 5-oxo-1-(phenylacetyl)-, trimethylsilyl ester

There total 3 articles about L-Proline, 5-oxo-1-(phenylacetyl)-, trimethylsilyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

triethylammonium salt of pyroglutamic acid (97635-54-6) → C16H21NO4Si (98062-32-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / toluene / 3 h / Heating

2: tetrahydrofuran / 1) reflux, 2 h, 2) RT, 5 h

In tetrahydrofuran; toluene;

DOI:10.1002/jhet.5570250109

Reference yield:

monosilylpyroglutamic acid (117316-37-7) → C16H21NO4Si (98062-32-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / toluene / 3 h / Heating

2: tetrahydrofuran / 1) reflux, 2 h, 2) RT, 5 h

In tetrahydrofuran; toluene;

DOI:10.1002/jhet.5570250109

Reference yield:

oxoproline TMS (30274-77-2) + phenylacetyl chloride (103-80-0) → C16H21NO4Si (98062-32-9)

Guidance literature:

In tetrahydrofuran; 1) reflux, 2 h, 2) RT, 5 h;

DOI:10.1002/jhet.5570250109

upstream raw materials:

oxoproline TMS

phenylacetyl chloride

triethylammonium salt of pyroglutamic acid

monosilylpyroglutamic acid

Downstream raw materials:

5-oxo-1-(phenylacetyl)-L-proline

Refernces