2-Chloro-5-methoxy-3-nitropyridine

Base Information

• Chemical Name: 2-Chloro-5-methoxy-3-nitropyridine
• CAS No.: 1003711-55-4
• Molecular Formula: C₆H₅ClN₂O₃
• Molecular Weight: 188.57
• Hs Code.: 2933399090
• Mol file: 1003711-55-4.mol

Synonyms:2-chloranyl-5-methoxy-3-nitro-pyridine;2-chloro-3-nitro-5-methoxypyridine;

Chemical Property of 2-Chloro-5-methoxy-3-nitropyridine

Chemical Property:

• Boiling Point: 316.2 °C at 760 mmHg
• Flash Point: 145 °C
• PSA: 67.94000
• Density: 1.445 g/cm³
• LogP: 2.17500
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Chloro-5-methoxy-3-nitropyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Use Description: 2-Chloro-5-methoxy-3-nitropyridine serves several roles in various fields. In the field of organic synthesis, it can be employed as an important intermediate in the manufacturing of pharmaceuticals, agrochemicals, and other fine chemicals. This compound's unique structure makes it valuable in the development of novel drugs and pesticides. In research and development, it plays a role as a building block for chemists working on the synthesis of more complex molecules. Its applications extend into the field of materials science, where it may be used in the creation of advanced materials with specific properties. Additionally, its presence in chemical laboratories aids in the advancement of scientific knowledge and innovation.

Technology Process of 2-Chloro-5-methoxy-3-nitropyridine

There total 2 articles about 2-Chloro-5-methoxy-3-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.1%

sodium methylate (124-41-4) + 2-chloro-5-fluoro-3-nitro pyridine (136888-21-6) → 2-chloro-5-methoxy-3-nitropyridine (1003711-55-4)

Guidance literature:

In methanol; at 0 - 50 ℃; for 2h;

Reference yield:

→ 2-chloro-5-methoxy-3-nitropyridine (1003711-55-4)

Guidance literature:

Reference yield:

2-chloro-5-methoxy-3-nitropyridine (1003711-55-4) + cyclohexylamine (108-91-8,157973-60-9) → C12H17N3O3

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; at 60 ℃;

upstream raw materials:

sodium methylate

2-chloro-5-fluoro-3-nitro pyridine

Refernces

• 1、 -. "Nitro, amino and aroylamino-N-phenylpyridinamines in a process for preparing pyrido[1,4]benzodiazepines". . . Retrieved 2008/06/13.