5-Bromo-4,6-dimethoxypyrimidine ,97%

Base Information

• Chemical Name: 5-Bromo-4,6-dimethoxypyrimidine ,97%
• CAS No.: 4319-77-1
• Molecular Formula: C6H7BrN2O2
• Molecular Weight: 219.03600
• Hs Code.: 2933599090
• Mol file: 4319-77-1.mol

Synonyms:5-bromo-4,6-dimethoxypyrimidine

Chemical Property of 5-Bromo-4,6-dimethoxypyrimidine ,97%

Chemical Property:

• Vapor Pressure: 0.00418mmHg at 25°C
• Melting Point: 149-151oC
• Boiling Point: 287.9oC at 760 mmHg
• PKA: -0.03±0.26(Predicted)
• Flash Point: 127.9oC
• PSA: 44.24000
• Density: 1.563g/cm3
• LogP: 1.25630
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

5-bromo-4,6-dimethoxypyrimidine ^*data from reagent suppliers

Safty Information:

• Statements: 34
• Safety Statements: 16-26-36/37/39-45

MSDS Files:

Useful:

Technology Process of 5-Bromo-4,6-dimethoxypyrimidine ,97%

There total 3 articles about 5-Bromo-4,6-dimethoxypyrimidine ,97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-bromo-4,6-dichloropyrimidine (68797-61-5) + sodium methylate (124-41-4) → 5-bromo-4,6-dimethoxypyrimidine (4319-77-1)

Guidance literature:

In methanol; at 20 ℃; for 1h;

Reference yield:

4,6-dimethoxypyrimidine (5270-94-0) → 5-bromo-4,6-dimethoxypyrimidine (4319-77-1)

Guidance literature:

With N-Bromosuccinimide; acetic anhydride; at 100 ℃; for 5.16h;

Reference yield:

→ 5-bromo-4,6-dimethoxypyrimidine (4319-77-1)

Guidance literature:

4,6-Dimethoxypyrimidin, N-Bromsuccinimid/Acetanhydrid;

upstream raw materials:

4,6-dimethoxypyrimidine

5-bromo-4,6-dichloropyrimidine

sodium methylate

Downstream raw materials:

4,6-dimethoxy-5-(3,4-dinitrophenyl)pyrimidine

Refernces

• 1、 -. "COMPOUNDS AS MODULATORS OF ROR GAMMA". Page/Page column 141-142. . Retrieved 2015/11/09.