(E)-N-Acetyl-N-desmethyl Doxepin

Base Information

• Chemical Name: (E)-N-Acetyl-N-desmethyl Doxepin
• CAS No.: 250331-54-5
• Molecular Formula: C20H21NO2
• Molecular Weight: 307.39
• Mol file: 250331-54-5.mol

Synonyms:N-[(3E)-3-Dibenz[b,e]oxepin-11(6H)-ylidenepropyl]-N-methylacetamide;

Chemical Property of (E)-N-Acetyl-N-desmethyl Doxepin

Chemical Property:

• Boiling Point: 486.0±44.0 °C(Predicted)
• PKA: -0.52±0.70(Predicted)
• PSA: 29.54000
• Density: 1.171±0.06 g/cm3(Predicted)
• LogP: 3.87910

Purity/Quality:

97% ^*data from raw suppliers

(E)-N-Acetyl-N-desmethylDoxepin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Doxepin (D550000) metabolite.

Technology Process of (E)-N-Acetyl-N-desmethyl Doxepin

There total 1 articles about (E)-N-Acetyl-N-desmethyl Doxepin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

doxepin hydrochloride (1229-29-4,25127-31-5) → (E)-N-desmethyl-N-formyldoxepin (250331-52-3) + (E)-N-acetyldidesmethyldoxepin (250331-53-4) + (E)-N-acetyl-N-desmethyldoxepin (250331-54-5)

Guidance literature:

Cunninghamella elegans (ATTC 9245); In Saline solution; at 26 ℃; for 96h;

upstream raw materials:

doxepin hydrochloride

Refernces