Z-D-Glu-OMe

Base Information

• Chemical Name: Z-D-Glu-OMe
• CAS No.: 47087-37-6
• Molecular Formula: C₁₃H₁₅NO₆
• Molecular Weight: 281.265
• Mol file: 47087-37-6.mol

Synonyms:Z-D-Aspartic acid α-methyl ester;Cbz-D-Aspartic acid alpha methyl ester;(R)-3-(benzyloxycarbonylamino)-4-methoxy-4-oxobutanoic acid;

Chemical Property of Z-D-Glu-OMe

Chemical Property:

• Vapor Pressure: 0 mmHg at 25°C
• Boiling Point: 498.943 °C at 760 mmHg
• PKA: 4.09±0.19(Predicted)
• Flash Point: 255.552 °C
• PSA: 101.93000
• Density: 1.305 g/cm3
• LogP: 1.32000
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

(R)-3-(((Benzyloxy)carbonyl)amino)-4-methoxy-4-oxobutanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Z-D-Glu-OMe

There total 1 articles about Z-D-Glu-OMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-Benzyloxycarbonyl aspartic acid methyl ester (4668-42-2,47087-37-6)

Guidance literature:

3-Benzyloxycarbonyl-5-oxo-oxazolidin-4-ylessigsaeure, Me., NaOCH3;

Reference yield: 84.0%

methanol (67-56-1) + N-Benzyloxycarbonyl aspartic acid methyl ester (4668-42-2,47087-37-6) → dimethyl ((benzyloxy)carbonyl)aspartate (114195-60-7)

Guidance literature:

With dimethylsulfide; tetrabutyl ammonium fluoride; In acetonitrile; at 20 ℃; for 7h; Inert atmosphere; Electrochemical reaction;

DOI:10.1002/cjoc.202100395

Reference yield: 59.0%

acycloguanosine (59277-89-3) + N-Benzyloxycarbonyl aspartic acid methyl ester (4668-42-2,47087-37-6) → 2-benzyloxycarbonylamino-succinic acid 4-[2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl] ester 1-methyl ester

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1081/SCC-100104050

Downstream raw materials:

methyl 2-(benzyloxycarbonylamino)acrylate

dimethyl ((benzyloxy)carbonyl)aspartate