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10-((tert-Butoxycarbonyl)amino)decanoic acid

Base Information Edit
  • Chemical Name:10-((tert-Butoxycarbonyl)amino)decanoic acid
  • CAS No.:173606-50-3
  • Molecular Formula:C15H29NO4
  • Molecular Weight:287.4
  • Hs Code.:2924199090
  • European Community (EC) Number:837-942-4
  • DSSTox Substance ID:DTXSID00401912
  • Wikidata:Q82205217
  • Mol file:173606-50-3.mol
10-((tert-Butoxycarbonyl)amino)decanoic acid

Synonyms:173606-50-3;Boc-10-Adc-OH;BOC-10-AMINODECANOIC ACID;10-((tert-Butoxycarbonyl)amino)decanoic acid;10-[(2-methylpropan-2-yl)oxycarbonylamino]decanoic Acid;10-(Boc-amino)decanoic acid;10-{[(tert-butoxy)carbonyl]amino}decanoic acid;10-(N-Boc-amino)decanoic Acid;SCHEMBL2702010;BOC-10-AMINODECANOICACID;DTXSID00401912;MFCD00270351;AKOS007930090;AB92445;AS-70153;BP-28241;CS-0131704;FT-0663433;D95455;EN300-201194;N-T-BUTYLOXYCARBONYL-10-AMINO-DECANOIC ACID;Z1505703853;Decanoic acid, 10-[[(1,1-dimethylethoxy)carbonyl]amino]-

Suppliers and Price of 10-((tert-Butoxycarbonyl)amino)decanoic acid
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 10-(N-Boc-amino)decanoicAcid
  • 5g
  • $ 1320.00
  • Labseeker
  • BOC-10-AMINODECANOICACID 95
  • 5g
  • $ 1138.00
  • JR MediChem
  • 10-(tert-butoxycarbonyl)decanoicacid 96%
  • 25g
  • $ 980.00
  • Iris Biotech GmbH
  • Boc-10-Adc-OH
  • 5 g
  • $ 1215.00
  • Iris Biotech GmbH
  • Boc-10-Adc-OH
  • 1 g
  • $ 303.75
  • Crysdot
  • 10-((tert-Butoxycarbonyl)amino)decanoicacid 97%
  • 10g
  • $ 805.00
  • Crysdot
  • 10-((tert-Butoxycarbonyl)amino)decanoicacid 97%
  • 5g
  • $ 403.00
  • Crysdot
  • 10-((tert-Butoxycarbonyl)amino)decanoicacid 97%
  • 25g
  • $ 1942.00
  • Biosynth Carbosynth
  • 10-(N-Boc-amino)decanoic acid
  • 5 g
  • $ 1638.00
  • Biosynth Carbosynth
  • 10-(N-Boc-amino)decanoic acid
  • 2 g
  • $ 900.90
Total 11 raw suppliers
Chemical Property of 10-((tert-Butoxycarbonyl)amino)decanoic acid Edit
Chemical Property:
  • Boiling Point:429.2 °C at 760 mmHg 
  • PKA:4.78±0.10(Predicted) 
  • Flash Point:213.3 °C 
  • PSA:75.63000 
  • Density:1.015 g/cm3 
  • LogP:4.10740 
  • Storage Temp.:Store at 0°C 
  • XLogP3:3.7
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:12
  • Exact Mass:287.20965841
  • Heavy Atom Count:20
  • Complexity:284
Purity/Quality:

99% *data from raw suppliers

10-(N-Boc-amino)decanoicAcid *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Canonical SMILES:CC(C)(C)OC(=O)NCCCCCCCCCC(=O)O
  • Description Boc-10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
  • Uses BOC-10-AMINODECANOIC ACID is an aliphatic carboxylic acid containing an amine protecting group,it is used as a reagent in the preparation of various pharmaceutical compounds.
Technology Process of 10-((tert-Butoxycarbonyl)amino)decanoic acid

There total 10 articles about 10-((tert-Butoxycarbonyl)amino)decanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium carbonate; In 1,4-dioxane; water; at 30 - 65 ℃; Reflux;
Guidance literature:
With sodium hydroxide; In water; tert-butyl alcohol; at 20 ℃; for 16h;
DOI:10.1021/ja903292v
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