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Technology Process of Desmethyl Erlotinib

Desmethyl Erlotinib

Base Information Edit
  • Chemical Name:Desmethyl Erlotinib
  • CAS No.:183320-51-6
  • Molecular Formula:C21H21N3O4 · HCl or C1513C6H21N3O4 · HCl
  • Molecular Weight:421.83
  • Hs Code.:
  • UNII:ZJ7FA2S8Q6
  • DSSTox Substance ID:DTXSID50596524
  • Mol file:183320-51-6.mol
Desmethyl Erlotinib

Synonyms:OSI-420

Suppliers and Price of Desmethyl Erlotinib
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • OSI420
  • 10mg
  • $ 435.00
  • Crysdot
  • OSI-420 98+%
  • 5mg
  • $ 84.00
  • Crysdot
  • OSI-420 98+%
  • 50mg
  • $ 420.00
  • Crysdot
  • OSI-420 98+%
  • 10mg
  • $ 147.00
  • ChemScene
  • DesmethylErlotinib(hydrochloride) 98.69%
  • 5mg
  • $ 144.00
  • ChemScene
  • DesmethylErlotinib(hydrochloride) 98.69%
  • 10mg
  • $ 252.00
  • ChemScene
  • DesmethylErlotinib(hydrochloride) 98.69%
  • 50mg
  • $ 642.00
  • Chemenu
  • 2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethan-1-olhydrochloride 98%
  • 50mg
  • $ 393.00
  • American Custom Chemicals Corporation
  • DESMETHYL ERLOTINIB 95.00%
  • 5MG
  • $ 499.47
  • American Custom Chemicals Corporation
  • DESMETHYL ERLOTINIB 95.00%
  • 2MG
  • $ 234.00
Total 25 raw suppliers
Chemical Property of Desmethyl Erlotinib Edit
Chemical Property:
  • PSA：85.73000 
  • LogP:3.62600 
  • Hydrogen Bond Donor Count:3
  • Hydrogen Bond Acceptor Count:7
  • Rotatable Bond Count:10
  • Exact Mass:415.1298839
  • Heavy Atom Count:29
  • Complexity:511
Purity/Quality:

98%,99%, *data from raw suppliers

OSI420 *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:COCCOC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCO.Cl
  • Uses OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. OSI 420 can be used in biological study of effects of cytochrome P 450 3A on pharmacokinetic interaction between erlotinib and docetaxel in rats.

Total 8 Pictures about this product

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