4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid

Base Information Edit

Chemical Name:4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid
CAS No.:123654-26-2
Molecular Formula:C9H8ClNO3
Molecular Weight:213.62
Hs Code.:2932999099
DSSTox Substance ID:DTXSID50442754
Nikkaji Number:J1.988.849E
Wikidata:Q72434371
Mol file:123654-26-2.mol

Synonyms:123654-26-2;4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid;4-AMINO-5-CHLORO-2,3-DIHYDRO-1-BENZOFURAN-7-CARBOXYLIC ACID;4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid;4-Amino-5-chloro-2,3-dihydrobenzo[b]furan-7-carboxylic acid;7-Benzofurancarboxylic acid, 4-amino-5-chloro-2,3-dihydro-;MFCD12923204;4-Amino-5-chlorocoumaran-7-carboxylic Acid;SCHEMBL1502018;4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylicacid;DTXSID50442754;KRMUVKSAOVLXLF-UHFFFAOYSA-N;AMY34926;BCP07807;AKOS016006919;CS-O-32073;PB24062;AC-28383;AS-19583;SY025646;CS-0051044;FT-0753298;J-004969;J-514392;4-amino-5-chlor-2,3-dihydro-7-benzofurancarboxylic acid;4-amino-5-chloro-2, 3-dihydrobenzo[b]furan-7-carboxylic acid

Suppliers and Price of 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylicAcid
2.5g
$ 120.00

TCI Chemical
4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid >97.0%(HPLC)(T)
200mg
$ 107.00

TCI Chemical
4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid >97.0%(HPLC)(T)
1g
$ 320.00

SynChem
4-AMINO-5-CHLORO-2,3-DIHYDROBENZOFURAN-7-CARBOXYLIC ACID 95%
1 g
$ 1450.00

SynChem
4-AMINO-5-CHLORO-2,3-DIHYDROBENZOFURAN-7-CARBOXYLIC ACID 95%
500 mg
$ 850.00

Matrix Scientific
4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid 95+%
1g
$ 1882.00

Crysdot
4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid 97%
1g
$ 49.00

Crysdot
4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid 97%
5g
$ 149.00

Chem-Impex
4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylicAcid,≥97%(HPLC) ≥97%(HPLC)
1G
$ 387.86

Chemenu
4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid 99%
1000g
$ 9600.00

Total 94 raw suppliers

Chemical Property of 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid Edit

Chemical Property:

Melting Point:242 °C(dec.)
Boiling Point:406.498 °C at 760 mmHg
PKA:4.45±0.20(Predicted)
Flash Point:199.643 °C
PSA：72.55000
Density:1.567 g/cm³
LogP:2.13650
Storage Temp.:2-8°C(protect from light)
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated)
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:213.0192708
Heavy Atom Count:14
Complexity:248

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C1C(=C(C=C2C(=O)O)Cl)N
Uses 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic Acid, can be used as an intermediate for the synthesis of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation.

Technology Process of 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid

There total 15 articles about 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%