(2S,4S)-Methyl4-(benzyloxycarbonylaMino)piperidine-2-carbo-xylate

Base Information

• Chemical Name: (2S,4S)-Methyl4-(benzyloxycarbonylaMino)piperidine-2-carbo-xylate
• CAS No.: 1255664-48-2
• Molecular Formula: C15H20N2O4
• Molecular Weight: 292.33
• Mol file: 1255664-48-2.mol

Synonyms:(2S,4S)-Methyl4-(benzyloxycarbonylaMino)piperidine-2-carbo-xylate

Chemical Property of (2S,4S)-Methyl4-(benzyloxycarbonylaMino)piperidine-2-carbo-xylate

Chemical Property:

• Boiling Point: 446.5±45.0 °C(Predicted)
• PKA: 11.77±0.40(Predicted)
• PSA: 80.15000
• Density: 1.20±0.1 g/cm3(Predicted)
• LogP: 1.73960
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

Methyl(2S,4S)-4-(benzyloxycarbonylamino)piperidine-2-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2S,4S)-Methyl4-(benzyloxycarbonylaMino)piperidine-2-carbo-xylate

There total 2 articles about (2S,4S)-Methyl4-(benzyloxycarbonylaMino)piperidine-2-carbo-xylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-oxo-piperidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester (81357-18-8,1799811-83-8) → C15H20N2O4 (1255664-48-2)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonium acetate

2: hydrogenchloride / water

With hydrogenchloride; ammonium acetate; In water;

DOI:10.1124/jpet.120.000258

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) + 1-(tert-butyl) 2-methyl 4-aminopiperidine-1,2-dicarboxylate → C15H20N2O4 (1255664-48-2)

Guidance literature:

With hydrogenchloride; In water;

DOI:10.1124/jpet.120.000258

upstream raw materials:

benzyl chloroformate

4-oxo-piperidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester

Refernces