7-epi-Taxol

Base Information Edit

Chemical Name:7-epi-Taxol
CAS No.:105454-04-4
Molecular Formula:C47H51 N O14
Molecular Weight:853.92
Hs Code.:2932999026
European Community (EC) Number:630-563-3
DSSTox Substance ID:DTXSID201318105
Nikkaji Number:J624.351G
Wikidata:Q104389133
Metabolomics Workbench ID:139980
ChEMBL ID:CHEMBL503883
Mol file:105454-04-4.mol

Synonyms:7 epi Taxol;7-epi-Taxol;Anzatax;Bris Taxol;NSC 125973;NSC-125973;NSC125973;Onxol;Paclitaxel;Paclitaxel, (4 alpha)-Isomer;Paxene;Praxel;Taxol;Taxol A;Taxol, Bris

Suppliers and Price of 7-epi-Taxol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-EpiPaclitaxel
100mg
$ 3195.00

Medical Isotopes, Inc.
7-11-Methano-1H-cyclodeca[3-4]benz[1-2-β]oxetebenzenepropanoicacidderivative
1 mg
$ 380.00

Medical Isotopes, Inc.
7-EpiPaclitaxel
5 mg
$ 2120.00

Matrix Scientific
7-Epitaxol 95+%
250mg
$ 3024.00

DC Chemicals
7-Epipaclitaxel >98%
1 g
$ 1600.00

Crysdot
7-Epitaxol 95+%
50mg
$ 283.00

Crysdot
7-Epitaxol 95+%
100mg
$ 444.00

ChemScene
7-epi-Taxol 99.85%
50mg
$ 350.00

ChemScene
7-epi-Taxol 99.85%
100mg
$ 550.00

ChemScene
7-epi-Taxol 99.85%
10mg
$ 110.00

Total 65 raw suppliers

Chemical Property of 7-epi-Taxol Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:168-170?C
Boiling Point:957.1°Cat760mmHg
PKA:11.90±0.20(Predicted)
Flash Point:532.6°C
PSA：221.29000
Density:1.39g/cm³
LogP:4.12660
Storage Temp.:Inert atmosphere,2-8°C
XLogP3:2.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:14
Exact Mass:853.33095530
Heavy Atom Count:62
Complexity:1790

Purity/Quality:

≥98% ^*data from raw suppliers

7-EpiPaclitaxel ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Isomeric SMILES:CC1=C2[C@H](C(=O)[C@@]3([C@@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Uses The compund has been isolated from Taxus brevifolia. It is an antineoplastic that is currently being used in cancer research. Paclitaxel EP Impurity E. 7-Epitaxol has been isolated from Taxus brevifolia. It is an antineoplastic that is currently being used in cancer research. Paclitaxel EP Impurity E.

Technology Process of 7-epi-Taxol

There total 20 articles about 7-epi-Taxol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 115437-19-9,133161-33-8,133161-34-9
2'-(1-Ethoxyethoxy)-7-triethylsilyltaxol

: 33069-62-4,105454-04-4,119323-97-6,147557-12-8,148553-70-2,149197-23-9
paclitaxel

Guidance literature:: With hydrogenchloride; In ethanol; at 0 ℃; for 48h;
DOI:10.1016/S0040-4020(01)91210-4

Reference yield: 86.0%

: 2',7-bis(monochloroacetyl)paclitaxel

: 33069-62-4,105454-04-4,119323-97-6,147557-12-8,148553-70-2,149197-23-9
paclitaxel

Guidance literature:: With thiourea; In ethanol; at 65 ℃; for 5h;
DOI:10.1021/jm00017a026

Reference yield: 82.0%

: 33069-62-4
taxol

: 105454-04-4
7-epipaclitaxel

Guidance literature:: With silver carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 3h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;