N-Hexadecanoyl-D-valine

Base Information

• Chemical Name: N-Hexadecanoyl-D-valine
• CAS No.: 132869-86-4
• Molecular Formula: C₂₁H₄₁NO₃
• Molecular Weight: 355.561
• Mol file: 132869-86-4.mol

Synonyms:N-n-hexadecanoyl (L)-valine;N-palmitoylvaline;N-palmitoyl-L-valine;

Chemical Property of N-Hexadecanoyl-D-valine

Chemical Property:

• PSA: 66.40000
• LogP: 6.08400

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: suzuki reaction

Technology Process of N-Hexadecanoyl-D-valine

There total 13 articles about N-Hexadecanoyl-D-valine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

palmitic acid N-succinimide ester (14464-31-4) + L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) → (S)-N-hexadecanoylvaline (83871-20-9,132869-86-4,45287-42-1)

Guidance literature:

With triethylamine; In ethanol; water; at 60 - 80 ℃; for 20h;

DOI:10.1039/c5ra10209j

Reference yield: 93.0%

N-n-hexadecanoyl methyl (L)-valinate (214706-35-1) → (S)-N-hexadecanoylvaline (83871-20-9,132869-86-4,45287-42-1)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; methanol; water; at 0 ℃; for 2h;

DOI:10.1016/j.tet.2007.05.028

Reference yield: 91.0%

D-Val-OH (640-68-6,25609-85-2,7004-03-7,921-10-8) + 4-nitrophenyl palmitate (1492-30-4) → N-palmitoyl-D-valine (132869-86-4)

Guidance literature:

With triethylamine; In 1,4-dioxane; water; at 60 ℃; for 7h;

DOI:10.1007/BF00958844

upstream raw materials:

D-Val-OH

4-nitrophenyl palmitate

1-hexadecylcarboxylic acid

L-valine

Downstream raw materials:

C₃₀H₅₀N₂O₄

Refernces

• 1、 -. "Organic compounds". Page/Page column 22; 23; 45; 46. . Retrieved 2020/11/23.
• 2、 Mandal, Subhra Kanti,Kar, Tanmoy,Das, Dibyendu,Das, Prasanta Kumar. "The striking influence of SWNT-COOH on self-assembled gelation". supporting information; body text. p. 1814 - 1816. Retrieved 2012/03/09.