1-(2-NAPHTHYL)ETHANOL

Base Information

• Chemical Name: 1-(2-NAPHTHYL)ETHANOL
• CAS No.: 40295-80-5
• Molecular Formula: C₁₂H₁₂O
• Molecular Weight: 172.227
• Mol file: 40295-80-5.mol

Synonyms:2-Naphthalenemethanol, alpha-methyl-, (±AURORA KA-6957;BETA-NAPHTHYL METHYL CARBINOL;(+/-)-1-(2-NAPHTHYL)ETHANOL;1-(2-NAPHTHYL)ETHANOL;2-(1-HYDROXYETHYL)NAPHTHALENE;ALPHA-METHYL-2-NAPHTHALENEMETHANOL;(+ -)-1-(2-NAPHTHYL)ETHANOL 99%

Chemical Property of 1-(2-NAPHTHYL)ETHANOL

Chemical Property:

• Melting Point: 73-78oC(lit.)
• PSA: 20.23000
• LogP: 2.89310

Purity/Quality:

98%min ^*data from raw suppliers

(+/-)-1-(2-NAPHTHYL)ETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2-NAPHTHYL)ETHANOL

There total 5 articles about 1-(2-NAPHTHYL)ETHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-ethylnaphthalene (939-27-5) → (+)-2-(1-hydroxyethane-1-yl)naphthalene (52193-85-8) + (-)-2-(1-hydroxyethane-1-yl)naphthalene (7228-47-9,27544-18-9,40295-80-5,52193-85-8) + methyl 2-naphthyl ketone (93-08-3)

Guidance literature:

With (-)-chloro-<5,10,15,20-tetrakis(1,2,3,4,5,6,7,8-octahydro-1,4:5,8-dimethanoanthracene-9-yl)porphirinato>manganese(III); iodosylbenzene; t-BuPy; In dichloromethane; for 14h; Product distribution;

DOI:10.1016/S0040-4020(97)00729-1

Reference yield:

methyl 2-naphthyl ketone (93-08-3) → (+)-2-(1-hydroxyethane-1-yl)naphthalene (52193-85-8) + (-)-2-(1-hydroxyethane-1-yl)naphthalene (7228-47-9,27544-18-9,40295-80-5,52193-85-8)

Guidance literature:

With (R,R)-C₇H₆SO₂C₁₄H₁₄N₂O₆S₂^(2-)*2Na⁽¹⁺⁾; sodium formate; sodium dodecyl-sulfate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; In water; at 40 ℃; for 24h; Title compound not separated from byproducts;

DOI:10.1021/ol0345125

Reference yield:

(S)-2-bromo-1-(2-naphthyl)ethyl acetate (117340-81-5) → (+)-2-(1-hydroxyethane-1-yl)naphthalene (52193-85-8) + (-)-2-(1-hydroxyethane-1-yl)naphthalene (7228-47-9,27544-18-9,40295-80-5,52193-85-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1021/jo00261a033

upstream raw materials:

(S)-2-bromo-1-(2-naphthyl)ethyl acetate

2-ethylnaphthalene

methyl 2-naphthyl ketone

2-bromo-1-(naphthalen-2-yl)ethan-1-ol

Refernces

• 1、 Halterman, Ronald L.,Jan, Shyi-Tai,Nimmons, Heather L.,Standlee, David J.,Khan, Masood A.. "Synthesis and catalytic reactivity of D4-symmetric dinorbornabenzene-derived metallotetraarylporphyrins". . p. 11257 - 11276. Retrieved 2007/10/03.