Cloricromen

Base Information

• Chemical Name: Cloricromen
• CAS No.: 68206-94-0
• Molecular Formula: C20H26ClNO5
• Molecular Weight: 395.8771
• European Community (EC) Number: 636-182-9
• UNII: B9454PE93C
• DSSTox Substance ID: DTXSID2048373
• Nikkaji Number: J22.686F
• Wikipedia: Cloricromen
• Wikidata: Q5135145
• NCI Thesaurus Code: C78091
• Metabolomics Workbench ID: 154183
• ChEMBL ID: CHEMBL255066
• Mol file: 68206-94-0.mol

Synonyms:8-chloro-3-beta-diethylaminoethyl-4-methyl-7-ethyoxycarbonymethoxycoumarin;8-chlorocarbochromen;8-chlorocarbochromen hydrochloride;8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarboxylmethoxycoumarin;AD 6;AD(6);AD6;cloricromen;cloricromene

Chemical Property of Cloricromen

Chemical Property:

• Vapor Pressure: 1.11E-10mmHg at 25°C
• Melting Point: 221-222.3 °C
• Refractive Index: 1.532
• Boiling Point: 514.1 °C at 760 mmHg
• Flash Point: 264.7 °C
• PSA: 68.98000
• Density: 1.189 g/cm³
• LogP: 3.58100
• Storage Temp.: 2-8°C
• Solubility.: DMSO: 17 mg/mL
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 10
• Exact Mass: 395.1499506
• Heavy Atom Count: 27
• Complexity: 561

Purity/Quality:

98%min ^*data from raw suppliers

Cloricromene ≥98% (HPLC), solid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCN(CC)CCC1=C(C2=C(C(=C(C=C2)OCC(=O)OCC)Cl)OC1=O)C
• Recent EU Clinical Trials: Double blind, randomized, multicenter, placebo-controlled, parallel-group design clinical trial of the efficacy and tolerability of cloriclomene hydrochloride capsules 100 mg TID in diabetic patients with mild to moderate non-proliferative retinopathy
• Description: Cloricromen is a new coumarin derivative useful as a coronary vasodilator and antithrombotic. It differs from existing antithrombotic agents in that it does not act chiefly on platelets. Cloricromen is reportedly well tolerated, improves exercise tolerance and decreases usage of nitrates by angina patients.