1-((Benzyloxy)methyl)-3-bromobenzene

Base Information

• Chemical Name: 1-((Benzyloxy)methyl)-3-bromobenzene
• CAS No.: 3395-75-3
• Molecular Formula: C₁₄H₁₃BrO
• Molecular Weight: 277.161
• DSSTox Substance ID: DTXSID10705938
• Wikidata: Q82639075
• Mol file: 3395-75-3.mol

Synonyms:1-((Benzyloxy)methyl)-3-bromobenzene;3395-75-3;1-[(Benzyloxy)methyl]-3-bromobenzene;SCHEMBL22469745;DTXSID10705938;AKOS010793922

Chemical Property of 1-((Benzyloxy)methyl)-3-bromobenzene

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 276.01498
• Heavy Atom Count: 16
• Complexity: 189

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COCC2=CC(=CC=C2)Br

Technology Process of 1-((Benzyloxy)methyl)-3-bromobenzene

There total 2 articles about 1-((Benzyloxy)methyl)-3-bromobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3-Bromophenyl)methanol (15852-73-0) + benzyl bromide (100-39-0) → 3-bromobenzyl, benzyl ether (3395-75-3)

Guidance literature:

(3-Bromophenyl)methanol; With sodium hydride; In N,N-dimethyl-formamide; for 0.5h; cooling;

benzyl bromide; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1039/b500037h

Reference yield:

(3-Bromophenyl)methanol (15852-73-0) → 3-bromobenzyl, benzyl ether (3395-75-3)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide;

DOI:10.1002/oms.1210161003

Reference yield:

3-bromobenzyl, benzyl ether (3395-75-3) → 1-(Azido-benzyloxy-methyl)-3-bromo-benzene + 1-(Azido-phenyl-methoxymethyl)-3-bromo-benzene

Guidance literature:

With [bis(acetoxy)iodo]benzene; trimethylsilylazide; In acetonitrile; at 25 ℃; for 1h; Further Variations:; Reagents; Temperatures; Product distribution;

DOI:10.1039/b500037h

upstream raw materials:

(3-Bromophenyl)methanol

benzyl bromide

Refernces

• 1、 Kingston, Eric E.,Shannon, James S.,Diakiw, Vladimir,Lacey, Michael J.. "Skeletal Rearrangements on Chemical Ionization of Dibenzyl Ether and Derivatives". . p. 428 - 440. Retrieved 2007/10/02.