Technology Process of (5'-Methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-carbaMic acid tert-butyl ester, 98+% C16H25N3O2, MW: 291.39
There total 1 articles about (5'-Methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-carbaMic acid tert-butyl ester, 98+% C16H25N3O2, MW: 291.39 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-Bromo-5-methylpyridine; tert‐butyl piperidin‐4‐ylcarbamate;
With
triethylamine;
In
dimethyl sulfoxide;
at 110 - 130 ℃;
for 23.5h;
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
In
dimethyl sulfoxide;
at 110 ℃;
for 17h;
- Guidance literature:
-
With
hydrogenchloride; methanol;
In
tetrahydrofuran; 1,4-dioxane;
at 20 ℃;
for 17h;