Cholan-24-oic acid, 3-hydroxy-7-(sulfooxy)-, (3a,5b,7b)-

Base Information

• Chemical Name: Cholan-24-oic acid, 3-hydroxy-7-(sulfooxy)-, (3a,5b,7b)-
• CAS No.: 74723-14-1
• Molecular Formula: C24H40O7S
• Mol file: 74723-14-1.mol

Synonyms:

Chemical Property of Cholan-24-oic acid, 3-hydroxy-7-(sulfooxy)-, (3a,5b,7b)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cholan-24-oic acid, 3-hydroxy-7-(sulfooxy)-, (3a,5b,7b)-

There total 3 articles about Cholan-24-oic acid, 3-hydroxy-7-(sulfooxy)-, (3a,5b,7b)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.2%

ursodeoxycholic acid (128-13-2) → 3,7-bis(sulfooxy)ursodeoxycholic acid (88426-32-8) + 7-hydroxy-3-(sulfooxy)-(3α,5β,7β)-cholan-24-oic acid (59132-32-0,64520-49-6,68780-68-7,68833-02-3,124815-69-6,68780-73-4) + 7-(sulfooxy)ursodeoxycholic acid (74723-14-1)

Guidance literature:

With pyridine; sulfur trioxide pyridine complex; at 0 - 20 ℃; for 0.166667h; other temperatures, other times, other reagent ratio;

Reference yield:

→ 7-Sulfo chenodeoxycholic-saeure (59132-31-9,74723-14-1,124690-05-7,124690-06-8,124690-07-9)

Guidance literature:

Dimethylchenodeoxycholat-3-hemisuccinat-7-sulfat (IIIa), milde alkalische Hydrolyse, NaOH / CH3OH;

DOI:10.1016/0039-128X(79)90127-2

Reference yield:

→ Chenodeoxycholsaeure-7-sulfat (59132-31-9,74723-14-1,124690-05-7,124690-06-8,124690-07-9)

Guidance literature:

Chenodeoxycholsaeure-methylester, 1) Ethylchlorcarbonat, 2) Chlorsulfonsaeure/Py.;

DOI:10.1016/0039-128X(77)90049-6

upstream raw materials:

ursodeoxycholic acid

Refernces