N-ACETYL-D-MANNOSAMINE

Base Information

• Chemical Name: N-ACETYL-D-MANNOSAMINE
• CAS No.: 4773-29-9
• Molecular Formula: C₈H₁₅NO₆
• Molecular Weight: 221.21
• Mol file: 4773-29-9.mol

Synonyms:Mannose,2-acetamido-2-deoxy- (6CI,8CI);N-Acetyl mannosamine;Acetyl-D-Mannosamine, N-;

Chemical Property of N-ACETYL-D-MANNOSAMINE

Chemical Property:

• Boiling Point: 636.4 °C at 760 mmHg
• PKA: 13.04±0.20(Predicted)
• Flash Point: 338.7 °C
• PSA: 127.09000
• Density: 1.423 g/cm³
• LogP: -2.84410
• Storage Temp.: −20°C

Purity/Quality:

98%, ^*data from raw suppliers

N-ACETYL-D-MANNOSAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-ACETYL-D-MANNOSAMINE

There total 9 articles about N-ACETYL-D-MANNOSAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetyl Coenzyme A + D-galactosamine (1948-54-5,2494-50-0,2636-92-2,3416-24-8,6915-39-5,7535-00-4,14307-02-9,14307-08-5,14307-09-6,14307-12-1,14307-14-3,14635-95-1,26315-48-0,27799-64-0,27799-65-1,69839-78-7,72904-60-0) → N-acetylgalactosamine (134-61-2,3615-17-6,4773-29-9,6813-82-7,7436-28-4,7512-17-6,20770-61-0,20880-43-7,20880-45-9,23583-38-2,23655-50-7,31022-50-1,50985-77-8,134451-94-8,149054-75-1,1811-31-0,282727-46-2,478518-83-1,127959-06-2,78393-48-3)

Guidance literature:

With human recombinant N-acetyltransferase; In aq. buffer; at 37 ℃; for 2h; pH=8; Enzymatic reaction;

DOI:10.1016/j.carres.2018.11.011

Reference yield:

2-acetamido-2-deoxy-D-glucose (7512-17-6,282727-46-2,478518-83-1,127959-06-2,78393-48-3) → N-acetylgalactosamine (134-61-2,3615-17-6,4773-29-9,6813-82-7,7436-28-4,7512-17-6,20770-61-0,20880-43-7,20880-45-9,23583-38-2,23655-50-7,31022-50-1,50985-77-8,134451-94-8,149054-75-1,1811-31-0,282727-46-2,478518-83-1,127959-06-2,78393-48-3)

Guidance literature:

With UDP-glucose 4-epimerase; N-acetylhexosamine 1-kinase; UDP-glucose-galactose 1-phosphate uridylyl transferase; ATP; magnesium chloride; at 30 ℃; for 120h; pH=6.5; aq. buffer; Enzymatic reaction;

DOI:10.1016/j.carres.2011.08.032

Reference yield:

heteropolysaccharide HPS4-2A from Radix Hedysari → L-arabinose (5328-37-0) + L-Rhamnose (3615-41-6,478518-52-4) + D-glucose (50-99-7) + D-Galactose (59-23-4) + N-acetylgalactosamine (134-61-2,3615-17-6,4773-29-9,6813-82-7,7436-28-4,7512-17-6,20770-61-0,20880-43-7,20880-45-9,23583-38-2,23655-50-7,31022-50-1,50985-77-8,134451-94-8,149054-75-1,1811-31-0,282727-46-2,478518-83-1,127959-06-2,78393-48-3)

Guidance literature:

With water; trifluoroacetic acid; at 121 ℃; for 3.5h;

DOI:10.1016/j.fitote.2013.05.011

upstream raw materials:

acetic anhydride

N-[(2R,3R,4R,5R,6R)-2-((S)-2,3-Dihydroxy-propoxy)-5-hydroxy-6-hydroxymethyl-4-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl]-acetamide

α-L-Fuc-(1-3)-β-D-GalNAc-(1-3)-β-D-Gal-(1-4)-β-D-Gal-(1-3)-D-GalNAc-ol

2-acetamido-2-deoxy-D-glucose

Downstream raw materials:

β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-D-galactose

Refernces

• 1、 Dang, Zilong,Feng, Demei,Liu, Xiaohua,Yang, Tao,Guo, Long,Liang, Jin,Liang, Jiandi,Hu, Fangdi,Cui, Fang,Feng, Shilan. "Structure and antioxidant activity study of sulfated acetamido- polysaccharide from Radix Hedysari". . p. 20 - 32. Retrieved 2013/10/22.
• 2、 Perepelov,Liu, Bin,Guo, Dan,Senchenkova,Shahskov,Feng, Lu,Wang, Lei,Knirel. "Structure elucidation of the O-antigen of Salmonella enterica O51 and its structural and genetic relation to the O-antigen of Escherichia coli O23". experimental part. p. 774 - 779. Retrieved 2012/01/19.