Technology Process of 1H-Indole-7-carboxylic acid, 3-[(dimethylamino)methyl]-, methyl ester
There total 5 articles about 1H-Indole-7-carboxylic acid, 3-[(dimethylamino)methyl]-, methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
eschenmoser's salt; methyl 1H-indole-7-carboxylate;
In
acetic acid;
at 65 ℃;
for 2h;
With
potassium carbonate;
In
dichloromethane;
at 20 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: HCl / 6 h / 80 °C
2: dimethylformamide / 6.5 h / 100 °C
3: H2 / 5percent Pd/C
4: acetic acid; dioxane; H2O / 20 °C
With
hydrogenchloride; hydrogen;
palladium on activated charcoal;
In
1,4-dioxane; water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1248/cpb.43.1692
- Guidance literature:
-
Multi-step reaction with 3 steps
1: dimethylformamide / 6.5 h / 100 °C
2: H2 / 5percent Pd/C
3: acetic acid; dioxane; H2O / 20 °C
With
hydrogen;
palladium on activated charcoal;
In
1,4-dioxane; water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1248/cpb.43.1692