phenylsulfamic acid

Base Information

• Chemical Name: phenylsulfamic acid
• CAS No.: 15790-84-8
• Molecular Formula: C6H7 N O3 S . Na
• Molecular Weight: 195.174
• Mol file: 15790-84-8.mol

Synonyms:Sulfamicacid, phenyl-, monosodium salt (8CI,9CI); Sodium phenylsulfamate

Chemical Property of phenylsulfamic acid

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.561g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of phenylsulfamic acid

There total 8 articles about phenylsulfamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

aniline (62-53-3) → sodium phenylsulfamate (15790-84-8)

Guidance literature:

With chlorosulfonic acid; triethylamine; In dichloromethane; at 0 ℃; for 2h;

DOI:10.1021/acs.orglett.6b01747

Reference yield: 90.0%

C6H7NO3S*C12H27N → sodium phenylsulfamate (15790-84-8)

Guidance literature:

With sodium iodide;

DOI:10.1002/cbic.201900673

Reference yield: 84.0%

aniline (62-53-3) → sodium phenylsulfamate (15790-84-8) + Dinatrium-Anilin-N,N-disulfonat (14568-96-8)

Guidance literature:

With 2-picoline sulfur trioxide complex; 1.) 17-18 deg C, 71 h;

DOI:10.1246/bcsj.59.952

upstream raw materials:

nitrobenzene

aniline

sodium sulfite

Downstream raw materials:

N-Benzyl-N'-phenylsulfamide

C₂₂H₂₄N₄O₈S

Refernces

• 1、 -. "STRAD-BINDING AGENTS AND USES THEREOF". Paragraph 1443-1445. . Retrieved 2021/08/06.
• 2、 Benedetti, Anna Mary,Gill, Daniel M.,Tsang, Chi W.,Jones, Alan M.. "Chemical Methods for N- and O-Sulfation of Small Molecules, Amino Acids and Peptides". . p. 938 - 942. Retrieved 2020/01/24.