2-Amino-4-methylthiazole hydrochloride

Base Information

• Chemical Name: 2-Amino-4-methylthiazole hydrochloride
• CAS No.: 6142-15-0
• Deprecated CAS: 68939-85-5
• Molecular Formula: C4H7ClN2S
• Molecular Weight: 150.632
• Hs Code.: 2934100090
• European Community (EC) Number: 692-375-8
• NSC Number: 265334
• UNII: W924D74VKE
• DSSTox Substance ID: DTXSID0064123
• Mol file: 6142-15-0.mol

Synonyms:2-Amino-4-methylthiazole hydrochloride;6142-15-0;4-methyl-1,3-thiazol-2-amine hydrochloride;4-Methyl-thiazol-2-ylamine hydrochloride;2-Thiazolamine, 4-methyl-, monohydrochloride;4-methylthiazol-2-amine hydrochloride;2-Amino-4-methylthiazole monohydrochloride;2-AMINO-4-METHYLTHIAZOLE HCl;Thiazole, 2-amino-4-methyl-, monohydrochloride;4-Methyl-2-thiazolamine hydrochloride;NSC 265334;4-methyl-1,3-thiazol-2-amine;hydrochloride;2-Thiazolamine, 4-methyl-, hydrochloride (1:1);NSC-265334;2-Thiazolamine, 4-methyl-, hydrochloride;SCHEMBL1966505;W924D74VKE;DTXSID0064123;4-Methyl-thiazol-2-ylamine HCl;4-METHYLTHIAZOL-2-AMINE HCL;MFCD00035214;NSC265334;AKOS005219957;AT13365;4-Methyl-2-thiazolamine monohydrochloride;AS-63632;2-Amino-4-methylthiazole, monohydrochloride;LS-150627;LS-150784;A0336;CS-0238235;FT-0649365;EN300-191814;A868708

Chemical Property of 2-Amino-4-methylthiazole hydrochloride

Chemical Property:

• Vapor Pressure: 0.0588mmHg at 25°C
• Melting Point: 173 °C
• Boiling Point: 232.5 °C at 760 mmHg
• Flash Point: 94.4 °C
• PSA: 67.15000
• LogP: 2.41690
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility.: almost transparency
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 150.0018471
• Heavy Atom Count: 8
• Complexity: 66.7

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Amino-4-methylthiazole Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CSC(=N1)N.Cl

Technology Process of 2-Amino-4-methylthiazole hydrochloride

There total 1 articles about 2-Amino-4-methylthiazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-oxothiazolidine-2-iminyl)thiazol-4-acetic acid ethyl ester (294886-88-7) → thiazoline-2,4-dione (2295-31-0) + 2-amino-4-methylthiazole hydrochloride (6142-15-0)

Guidance literature:

With hydrogenchloride; In water; Heating;

Reference yield: 89.0%

2-amino-4-methylthiazole hydrochloride (6142-15-0) → 5-bromo-4-methyl-thiazol-2-ylamine; hydrochloride (133692-16-7)

Guidance literature:

With N-Bromosuccinimide; acetic acid; Ambient temperature;

DOI:10.1016/S0960-894X(98)00404-1

Reference yield:

2-amino-4-methylthiazole hydrochloride (6142-15-0) → 5-chloro-4-methylthiazol-2-amine (5316-76-7)

Guidance literature:

With chlorine; acetic acid;

upstream raw materials:

2-(4-oxothiazolidine-2-iminyl)thiazol-4-acetic acid ethyl ester

Downstream raw materials:

5-chloro-4-methylthiazol-2-amine

(4-methyl-thiazol-2-yl)-urea

5-bromo-4-methyl-thiazol-2-ylamine; hydrochloride

N-(4-{[(4-methyl-2-thiazolyl)amino]sulfonyl}phenyl)-acetamide

Refernces