2-AMino-5-cyano-N,3-diMethylbenzaMide

Base Information

• Chemical Name: 2-AMino-5-cyano-N,3-diMethylbenzaMide
• CAS No.: 890707-29-6
• Molecular Formula: C₁₀H₁₁N₃O
• Molecular Weight: 189.217
• Hs Code.: 2926909090
• Mol file: 890707-29-6.mol

Synonyms:2-AMino-5-cyano-N,3-diMethylbenzaMide;Benzamide, 2-amino-5-cyano-N,3-dimethyl-;2-Amino-5-cyano-N-methyl-3-methylbenzamide

Chemical Property of 2-AMino-5-cyano-N,3-diMethylbenzaMide

Chemical Property:

• Boiling Point: 359.2±42.0 °C(Predicted)
• PKA: 14.57±0.46(Predicted)
• PSA: 82.40000
• Density: 1.20±0.1 g/cm3(Predicted)
• LogP: 1.96448
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99.9% ^*data from raw suppliers

2-Amino-5-cyano-N,3-dimethylbenzamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Amino-5-cyano-N-methyl-3-methylbenzamide is an impurity of Cyantraniliprole (C987580), which belongs to the cyano anthranilamide and has activity against invertebrated pests. This family of insect control chemicals activate de cyanodine receptors causing mortality.

Technology Process of 2-AMino-5-cyano-N,3-diMethylbenzaMide

There total 28 articles about 2-AMino-5-cyano-N,3-diMethylbenzaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-amino-5-bromo-N,3-dimethylbenzamide (890707-30-9) + sodium cyanide (143-33-9,25596-52-5) → N-methyl-3-methyl-2-aminobenzamide (870997-57-2) + 2-amino-3-methyl-5-cyanobenzoyl-N-methylamine (890707-29-6)

Guidance literature:

With polymethylhydrosiloxane; [(1,1′-bis(diphenylphosphino)ferrocene)Ni⁽⁰⁾(1,5-cyclooctadiene)]; In acetonitrile; at 70 - 72 ℃; for 3h; Product distribution / selectivity;

Reference yield: 95.0%

2-methoxyethyl 2-amino-5-cyano-3-methylbenzoate (1417858-32-2) + methylamine (74-89-5) → 2-amino-3-methyl-5-cyanobenzoyl-N-methylamine (890707-29-6)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 18h;

Reference yield: 91.4%

2-ethylhexyl 2-amino-5-cyano-3-methylbenzoate (1417858-29-7) + methylamine (74-89-5) → 2-amino-3-methyl-5-cyanobenzoyl-N-methylamine (890707-29-6)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 18h;

upstream raw materials:

2-amino-5-bromo-N,3-dimethylbenzamide

dicyanozinc

sodium cyanide

2-amino-3-methyl-5-chlorobenzoyl-N-methylamine

Refernces

• 1、 -. "A PROCESS FOR THE SYNTHESIS ANTHRANILIC DIAMIDE COMPOUNDS AND INTERMEDIATES THEREOF". . . Retrieved 2020/09/08.
• 2、 -. "METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE". Paragraph 0103; 0104; 0108. . Retrieved 2014/06/11.